Results 51 to 60 of about 4,412,175 (293)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Self-recovery of memory via generative replay

open access: yesCoRR, 2023
A remarkable capacity of the brain is its ability to autonomously reorganize memories during offline periods. Memory replay, a mechanism hypothesized to underlie biological offline learning, has inspired offline methods for reducing forgetting in artificial neural networks in continual learning settings. A memory-efficient and neurally-plausible method
Zhenglong Zhou   +2 more
openaire   +2 more sources

Collegiate Recovery Students and Programs: Literature Review from 1988-2017

open access: yes, 2018
Objectives: To present a review of the existing research on college students living in recovery, including the research on students in recovery participating in collegiate recovery programs.   Methods: Studies were included if they: a) were ...
Brown, Austin   +4 more
core   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Recovery ... reporting overview; Connecticut recovery; CT recovery ... progress

open access: yes, 2010
Updated quarterly; Began in 2009.; Title from home page last modified 10/29/2009 (viewed Oct. 29, 2009).; At head of title: State of Connecticut.; "On October 1, state agencies that have received Recovery Act funds began reporting to the federal ...

core   +1 more source

An MCM-Enhanced Compressive Sensing for Weak Fault Feature Extraction of Rolling Element Bearings under Variable Speeds

open access: yesShock and Vibration, 2020
The compressive sensing (CS) theory provides a new slight to the big-data problem led by the Shannon sampling theorem in rolling element bearings condition monitoring, where the measurement matrix of CS tends to be designed by the random matrix (RM) to ...
Ya He, Kun Feng, Minghui Hu, Jinmiao Cui
doaj   +1 more source

A Low Distortion Audio Self-Recovery Algorithm Robust to Discordant Size Content Replacement Attack

open access: yesComputers, 2021
Although the development of watermarking techniques has enabled designers to tackle normal processing attacks (e.g., amplitude scaling, noise addition, re-compression), robustness against malicious attacks remains a challenge. The discordant size content
Juan Jose Gomez-Ricardez   +1 more
doaj   +1 more source

Findings from Transforming Youth Recovery’s 2017 Recovery Census

open access: yes, 2018
In 2013, Transforming Youth Recovery (TYR) published the 38 Assets for Building Collegiate Recovery Capacity as a guide for its early stage grant program, Seeds of Hope.
Jones, Erin K
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

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