Results 61 to 70 of about 6,849,826 (296)

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Dynamic-Decoupling Robust Integral Sliding-Mode Control for Performance-Degraded Electromagnetic Actuators

open access: yesIEEE Access
This paper proposes an adaptive robust integral sliding-mode control (ARISMC) strategy centered on dynamic decoupling to address control-performance degradation in electromagnetic actuators for reciprocating compressors caused by coil aging and spring ...
Xu Li   +4 more
doaj   +1 more source

A fault current limiting control scheme for sectionalized connection mode based on dynamic topology adjustment

open access: yesZhejiang dianli, 2022
With the rapid development of the power grid, the overhigh short-circuit current becomes increasingly prominent, restricting the safe and stable power grid operation.
ZHOU Qiwen   +5 more
doaj   +1 more source

Recovery from first-episode psychosis and recovering self: A qualitative study [PDF]

open access: yes, 2015
Objective\ud \ud The objective of this study was to explore the subjective factors associated with the experience of first-episode psychosis (FEP) and the very first stages of recovery to develop our understanding of this process and improve treatment ...
Schweitzer, Robert D.   +2 more
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

An MCM-Enhanced Compressive Sensing for Weak Fault Feature Extraction of Rolling Element Bearings under Variable Speeds

open access: yesShock and Vibration, 2020
The compressive sensing (CS) theory provides a new slight to the big-data problem led by the Shannon sampling theorem in rolling element bearings condition monitoring, where the measurement matrix of CS tends to be designed by the random matrix (RM) to ...
Ya He, Kun Feng, Minghui Hu, Jinmiao Cui
doaj   +1 more source

Building Capacity for Recovery Support at Institutions of Higher Education [PDF]

open access: yes, 2018
Capacitype™ data and mapping services help groups and organizations build capacity for recovery in their communities. The simple idea behind Capacitype is to invite everyone to go out and map assets – those people, places, and services that people are ...
Hart, Christopher D
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Self-care in mental health services: a narrative review [PDF]

open access: yes, 2011
Self-care is an important approach to the management of long-term health conditions and in preventing ill-health by living a healthy lifestyle. The concept has been used to a limited extent in relation to mental health, but it overlaps with the related ...
Simons, Lucy   +12 more
core   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

open access: yesFEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Home - About - Disclaimer - Privacy