Results 51 to 60 of about 1,040,224 (263)
Hibridisme i autoreferència en el fantàstic d’Espiral, de Manuel Baixauli
The aim of this paper is to define and to analyse the fantastic universe of short stories by Manuel Baixauli published in the volume Espiral (2010), an original and highly significant example of modern fantastic literature that has ...
Carme Gregori Soldevila
doaj +3 more sources
Formaliser le trope. De la subjectivité linguistique à la subjectivité épilinguistique
Usually associated with notions such as deviation, relevance, or salience, the trope is often described as simultaneously singular and ordinary. In order to invalidate this paradox, our contribution further analyzes the operations which enable the ...
Adrien Mathy
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Submorphemes: backtracking from English ‘kn- words’ to the emergence of the linguistic sign
I claim, within a semiogenetic theory of the conditions of emergence and evolution of the linguistic sign (STEELS), that the polysemy exhibited by Modern English ‘kn- words’ related to body-joints and their actions (knead, knee, knuckle, etc.) is a ...
Dennis Philps
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Bateson Information Revisited: A New Paradigm
The goal of this work is to explain a novel information paradigm claiming that all information results from a process, intrinsic to living beings, of self-production; a sensory commensurable, self-referential feedback process immanent to Bateson’s ...
Jaime F. Cárdenas-García +1 more
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Orders of the Division of Labor: Self-reference in Organization Structures
As a consequence of a variety of dynamics that firms have to deal with, their structures are continually evolving. Some of the resulting patterns and structural properties, however, only become visible at a greater distance from the object of analysis ...
Meisinger Norman
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Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source

