Results 51 to 60 of about 3,327,094 (298)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Implementation of Prisoners' Self-Guidance Development at Penitentiary Institutions to Eradicate Negative Stigma

open access: yesBisma The Journal of Counseling, 2020
In Law 12 of 1995 concerning Correctional, it is explained that the convict is someone who has obtained permanent legal force from the court for violating the law he commited and placed in a correctional institution. In undergoing their criminal term in
Dewa Dermawan Febrianto
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Confiance en soi et métamorphose éducative

open access: yesRecherches en Éducation, 2018
This article investigates how, in education, self-reliance has been underpinned by trust in the educator. By distinguishing confidence and seduction, one returns to education its original project to lead the subjects towards the emancipation.
Didier Moreau
doaj   +1 more source

The Concept of Self-Reliance

open access: yesInternational Journal of Humanities and Social Science, 2022
Self-reliance is the ability that is owned within self that combines with the abilities of other individuals who form cooperation in order to realize progress/increase in welfare. Self-reliant individuals can get what they want through their own efforts and combine their own efforts and the efforts of others to achieve the greatest success together.
openaire   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

CONCEPT OF SIMPLE LIFE BY H. D.THOREAU

open access: yesLìteraturnij Proces: Metodologìâ, Ìmena, Tendencìï, 2019
In this study, the author examines the concept of “simple life” in the work “Walden; or Life in the Woods” by H. D. Thoreau in the context of transcendental philosophy. The article gives a brief overview of R. Emerson’s works on transcendentalism (which
Kyrylo Ihoshev
doaj   +1 more source

Final Report: The self Reliance Foundation and Hispanic Radio Network Collaborative, September 30, 1995 - January 31, 1998

open access: yes, 1998
The Self Reliance Foundation, through its production subcontractor, Hispanic Radio Network, produced daily 1-3 minute radio capsules on science, education, and the environment. The programs were broadcast on over 100 U.S.
Multedo, Molly
core   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

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