Results 61 to 70 of about 4,764,551 (287)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Award reliance [PDF]

open access: yes, 2013
The study was conducted by the Workplace Research Centre, University of Sydney in collaboration with fieldwork company ORC International on behalf of the Fair Work Commission.
Buchanan, John   +3 more
core  

Interior Design Enhancing Accessibility for the Disabled: Improving Quality of Life through Smart Innovations [PDF]

open access: yesMSA Engineering Journal
Individuals with disabilities often face challenges in their daily activities, limiting their independence and reducing their overall quality of life, particularly in public spaces where their needs may be overlooked. This paper explores how interior and
Yousif SalahEldeen
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Combating Poverty Through Self Reliance: The Islamic Approach [PDF]

open access: yes
Poverty comes at the head of man’s present plight hence, the need to combat it. Self-reliance as a mean of eradicating poverty has become a concept central to Nigeria’s policy in recent years. The major problem of the policy however, is that its approach
Ahmad Bello, Dogarawa
core  

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Uganda’s approach to refugee self-reliance

open access: yesForced Migration Review, 2016
Uganda has chosen inclusion over marginalisation; rather than coerce refugees into camps, Uganda upholds their rights to work, to attend school and to move freely.
Kelly T Clements   +2 more
doaj  

Confiance en soi et métamorphose éducative

open access: yesRecherches en Éducation, 2018
This article investigates how, in education, self-reliance has been underpinned by trust in the educator. By distinguishing confidence and seduction, one returns to education its original project to lead the subjects towards the emancipation.
Didier Moreau
doaj   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

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