Results 91 to 100 of about 5,141,384 (392)

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano   +11 more
wiley   +1 more source

The elements of stem cell self-renewal: a genetic perspective

open access: yesBioTechniques, 2003
Every day, the body produces billions of new blood cells. Each of these is derived from a rare cell in the bone marrow called the hematopoietic stem cell (HSC).
Gregory Pazianos   +2 more
doaj   +1 more source

MYC regulates the HIF-2α stemness pathway via Nanog and Sox2 to maintain self-renewal in cancer stem cells versus non-stem cancer cells.

open access: yesCancer Research, 2019
Cancer stem cells (CSC) maintain both undifferentiated self-renewing CSCs and differentiated, non-self-renewing non-CSCs through cellular division. However, molecular mechanisms that maintain self-renewal in CSCs versus non-CSCs are not yet clear.
Bikul Das   +14 more
semanticscholar   +1 more source

MENINGKATKAN ADVANCED MATHEMATICAL THINKING DAN SELF-RENEWAL CAPACITY MAHASISWA MELALUI PEMBELAJARAN MODEL PACE [PDF]

open access: yes, 2016
Tujuan utama penelitian ini adalah untuk menganalisis secara komprehensif pencapaian dan peningkatan Advanced Mathematical Thinking dan Self-Renewal Capacity mahasiswa sebagai akibat dari implementasi pembelajaran Model PACE (Proyek, Aktivitas ...
Suryana, Andri
core  

cMyc Regulates the Size of the Premigratory Neural Crest Stem Cell Pool [PDF]

open access: yes, 2016
The neural crest is a transient embryonic population that originates within the central nervous system (CNS) and then migrates into the periphery and differentiates into multiple cell types.
Bronner, Marianne E., Kerosuo, Laura
core   +2 more sources

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall   +16 more
wiley   +1 more source

Two major gate-keepers in the self-renewal of neural stem cells: Erk1/2 and PLCγ1 in FGFR signaling

open access: yesMolecular Brain, 2009
Neural stem cells are undifferentiated precursor cells that proliferate, self-renew, and give rise to neuronal and glial lineages. Understanding the molecular mechanisms underlying their self-renewal is an important aspect in neural stem cell biology ...
Lee Jin-A   +2 more
doaj   +1 more source

Trim71 cooperates with microRNAs to repress Cdkn1a expression and promote embryonic stem cell proliferation [PDF]

open access: yes, 2012
Pluripotent embryonic stem cells (ESCs) have a shortened cell cycle that enables their rapid proliferation. The ESC-specific miR-290 and miR-302 microRNA families promote proliferation whereas let-7 microRNAs inhibit self-renewal and promote cell ...
Chang, Hao-Ming   +3 more
core   +1 more source

Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati   +10 more
wiley   +1 more source

Homeostatic Epidermal Stem Cell Self-Renewal Is Driven by Local Differentiation.

open access: yesCell Stem Cell, 2018
Maintenance of adult tissues depends on sustained activity of resident stem cell populations, but the mechanisms that regulate stem cell self-renewal during homeostasis remain largely unknown.
Kailin R. Mesa   +7 more
semanticscholar   +1 more source

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