Results 351 to 360 of about 5,141,384 (392)
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Hematopoietic stem cell self-renewal
Current Opinion in Genetics & Development, 2006Recent studies have begun to elucidate the mechanisms controlling hematopoietic stem cell (HSC) self-renewal. Self-renewal requires the integration of survival signals and proliferation controls with the maintenance of an undifferentiated state. This demands a complex crosstalk between extrinsic signals from the microenvironment and the cell-intrinsic ...
Omobolaji O, Akala, Michael F, Clarke
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Long Range Planning, 1969
Abstract In this article President Haggerty of Texas Instruments discusses the problem: How can an organization become older and yet stay flexible and adaptable. He explains how at Texas Instruments he has tried to develop a system or framework within which continuous innovation, renewal and rebirth can occur.
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Abstract In this article President Haggerty of Texas Instruments discusses the problem: How can an organization become older and yet stay flexible and adaptable. He explains how at Texas Instruments he has tried to develop a system or framework within which continuous innovation, renewal and rebirth can occur.
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IEEE Internet Computing, 2011
Software practice has suffered from and continues to suffer from many shortcomings as a result. Programs are difficult to design and build; they often fail to satisfy user requirements. If they work adequately at all, it's more often due to users adapting to the program than the program meeting users' requirements.
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Software practice has suffered from and continues to suffer from many shortcomings as a result. Programs are difficult to design and build; they often fail to satisfy user requirements. If they work adequately at all, it's more often due to users adapting to the program than the program meeting users' requirements.
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New Directions for Higher Education, 1985
AbstractSuccessful strategies often take into account the apparently incompatible strengths and opportunities of the institution.
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AbstractSuccessful strategies often take into account the apparently incompatible strengths and opportunities of the institution.
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NASSP Bulletin, 1972
America's secondary schools are where the action is, and their administrators are subject to pressure from all directions. The author addresses himself to the nature and context of the intense demand for renewal in educational administration.
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America's secondary schools are where the action is, and their administrators are subject to pressure from all directions. The author addresses himself to the nature and context of the intense demand for renewal in educational administration.
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International Library Review, 1978
The British University Grants Committee, responsible for the allocation of government monies to the universities, was recently plied with a number of requests for grants for new library buildings or extensions to library buildings. In this situation, the Committee set up a working party under the chairmanship of Professor Atkinson, on capital provision
P. Havard-Williams, Anne Gilman
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The British University Grants Committee, responsible for the allocation of government monies to the universities, was recently plied with a number of requests for grants for new library buildings or extensions to library buildings. In this situation, the Committee set up a working party under the chairmanship of Professor Atkinson, on capital provision
P. Havard-Williams, Anne Gilman
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Oncogenes, self-renewal and cancer
Pathologie Biologie, 2006Cancers arise in a tissue as the culmination of a series of mutations that activate oncogenes and inactivate tumor suppressor genes. Many of these mutations affect cell proliferation and survival. Recently, it has become apparent that some oncogenes and tumor suppressor genes also regulate self-renewal, the process by which stem cells maintain ...
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2012
Recent research has acknowledged the key role of information systems (IS) in helping build sustainable organizations. Although many organizations have implemented strategies for increased sustainability, empirical evidence for the effects of such strategies is sparse, and the understanding of the underlying processes to reach ecoeffectiveness is ...
Hedman, Jonas +2 more
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Recent research has acknowledged the key role of information systems (IS) in helping build sustainable organizations. Although many organizations have implemented strategies for increased sustainability, empirical evidence for the effects of such strategies is sparse, and the understanding of the underlying processes to reach ecoeffectiveness is ...
Hedman, Jonas +2 more
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1998
The mechanisms that regulate the fate of hematopoietic stem cells are poorly understood. Hematopoietic growth factors and factors in the microenvironment are clearly essential for ensuring the survival and differentiation of hematopoietic stem cells, but their role in the selection between self-renewal and lineage commitment options is unclear ...
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The mechanisms that regulate the fate of hematopoietic stem cells are poorly understood. Hematopoietic growth factors and factors in the microenvironment are clearly essential for ensuring the survival and differentiation of hematopoietic stem cells, but their role in the selection between self-renewal and lineage commitment options is unclear ...
openaire +2 more sources