Results 101 to 110 of about 10,819,440 (309)
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
On the self‐similar heat boundary layer problems in magnetohydrodynamics
Mathematical Modelling and Analysis, 2002 Usually all self‐similar heat boundary layer problems in presence of magnetic field are solved neglecting the Joule heat, created by current, induced in fluid by interaction of velocity and magnetic field.
V. Kremenetsky
doaj +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
The 'Operational' Definition of Self-Control [PDF]
, 2018 Self-control is a hot topic across disciplines. As such, consensus on defining self-control is critical for advancing both scientific progress as well as societal impact of research findings.
Stress and self-regulation +3 more
core +1 more source
Equivalence of Self-similar and Pseudo-self-similar Tiling Spaces in ℝ2 [PDF]
Discrete & Computational Geometry, 2011 Given a tiling T, one may form a related tiling, called the derived Voronoi tiling of T, based on a patch of tiles in T. Similarly, for a tiling space X, one can identify a patch which appears regularly in all tilings in X, and form a derived Voronoi space of tilings, based on that patch.
openaire +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
Diffusion Cascades and Mutually Coupled Diffusion Processes
MathematicsIn this paper, we define and investigate a system of coupled regular diffusion equations in which each concentration acts as a driving term in the next diffusion equation.
Imre Ferenc Barna, László Mátyás
doaj +1 more source
A self-similar sine-cosine fractal architecture for multiport interferometers. [PDF]
Nanophotonics, 2023 Basani JR +4 more
europepmc +1 more source