Results 101 to 110 of about 8,164,309 (315)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

On the self‐similar heat boundary layer problems in magnetohydrodynamics

open access: yesMathematical Modelling and Analysis, 2002
Usually all self‐similar heat boundary layer problems in presence of magnetic field are solved neglecting the Joule heat, created by current, induced in fluid by interaction of velocity and magnetic field.
V. Kremenetsky
doaj   +1 more source

Inhomogeneous self-similar sets and measures

open access: yes, 2009
The thesis consists of four main chapters. The first chapter includes an introduction to inhomogeneous self-similar sets and measures. In particular, we show that these sets and measures are natural generalizations of the well known self-similar sets ...
Snigireva, Nina
core  

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Equivalence of Self-similar and Pseudo-self-similar Tiling Spaces in ℝ2 [PDF]

open access: yesDiscrete & Computational Geometry, 2011
Given a tiling T, one may form a related tiling, called the derived Voronoi tiling of T, based on a patch of tiles in T. Similarly, for a tiling space X, one can identify a patch which appears regularly in all tilings in X, and form a derived Voronoi space of tilings, based on that patch.
openaire   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Diffusion Cascades and Mutually Coupled Diffusion Processes

open access: yesMathematics
In this paper, we define and investigate a system of coupled regular diffusion equations in which each concentration acts as a driving term in the next diffusion equation.
Imre Ferenc Barna, László Mátyás
doaj   +1 more source

A self-similar sine-cosine fractal architecture for multiport interferometers. [PDF]

open access: yesNanophotonics, 2023
Basani JR   +4 more
europepmc   +1 more source

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