Results 81 to 90 of about 10,819,440 (309)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Modeling of Self-similar Traffic
Proceedings of the International Conference on Applied Innovations in IT, 2016 Modeling of self-similar traffic is performed for the queuing system of G/M/1/K type using Weibull distribution. To study the self-similar traffic the simulation model is developed by using SIMULINK software package in MATLAB environment.
Irina Strelkovskaya +2 more
doaj +1 more source
The categorical theory of self-similarity
Theory and Applications of Categories, 1999 This was published in Theory and Applications of Categories, an online open-access journal. http://www.tac.mta.ca/tac/index.html#vol6 It is uploaded here for the purposes of creating a DOI..
openaire +3 more sources
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
On self-similar axion-dilaton configurations
Journal of High Energy Physics, 2020 We explore self-similar collapse solutions to the Einstein-axion-dilaton system in arbitrary spacetime dimensions, which are invariant under spacetime dilation combined with internal SL(2, ℝ) transformations.
Riccardo Antonelli, Ehsan Hatefi
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Self similar solutions of generalized Burgers equation
Electronic Journal of Differential Equations, 2005 In this paper, we study the initial-value problem $$displaylines{ (|u'|^{p-2}u')'+eta r u'+alpha u-gamma |u|^{q-1}u|u'|^{p-2}u'=0, quad r greater than 0, cr u(0)=A,quad u'(0)=0, }$$ where $A$ greater than 0, $p$ greater than 2, $q greater than 1, $alpha ...
Abdelilah Gmira +2 more
doaj
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
The Ubiquity of Statistical Fractal Observations
Recoletos Multidisciplinary Research Journal, 2013 The natural world is recognized to be fractal: from the growth of a leaf to how the trees propagate to form a forest, the neural networks, the DNA and the galaxies in space.
Roberto N. Padua, Randy K. Salazar
doaj +1 more source