Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen +7 more
wiley +1 more source
Evidence of Iron Accumulation in Cerebral Adrenoleukodystrophy: A Potential Novel Disease Mechanism
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT In this first application of Quantitative Susceptibility Mapping Source Separation to cerebral adrenoleukodystrophy, we uncovered alterations in iron and myelin within lesions and normal appearing white matter. As validation, we demonstrate abnormal iron accumulation in those same compartments within primary brain tissue.
Christina L. Nemeth +8 more
wiley +1 more source
Use of Team-Based Learning Pedagogy to Prepare for a Pharmacy School Accreditation Self-Study. [PDF]
Pharmacy (Basel), 2021 Vinall R, Malhotra A, Puglisi J.
europepmc +1 more source
Annals of Clinical and Translational Neurology, EarlyView.Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao +6 more
wiley +1 more source
Reflecting on Responsible Conduct of Research: A Self Study of a Research-Oriented University Community. [PDF]
J Acad Ethics, 2022 Hite RL, Shin S, Lesley M.
europepmc +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang +8 more
wiley +1 more source
Chatbots as a Tool to Scale Mentoring Processes: Individually Supporting Self-Study in Higher Education. [PDF]
Front Artif Intell, 2021 Neumann AT +8 more
europepmc +1 more source
Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli +5 more
wiley +1 more source
Meshing the Personal with the Professional: Digital Storytelling in Higher Education
Seminar.net, 2010 This paper chronicles a yearlong journey of learning about digital storytelling and leading the creation of five digital stories within a higher education community.
Mary F. Wright, Karen Ryan
doaj
Impact of guided self-study on learning success in undergraduate physiotherapy students in Switzerland - a feasibility study of a higher education intervention. [PDF]
BMC Med Educ, 2021 Rogan S, Taeymans J, Zuber S, Zinzen E.
europepmc +1 more source