Results 121 to 130 of about 856,149 (315)

Metabolic and Microvascular Risk Factors Associated With Brain Health in Type 1 Diabetes

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We examined relationships between metabolic factors, microvascular complications, and brain health in adults with type 1 diabetes. Fifty‐one adults were assessed for metabolic risk factors, microvascular complications, and cognitive function, with a subset completing brain MRI.
Jihyun Park   +7 more
wiley   +1 more source

The affective characteristics of underachieving intellectually gifted children

open access: yes, 2006
Underachievement has long been recognised as a problem for some gifted children. In such cases, the potential of these children may be a loss to society.
Craven, Rhonda   +2 more
core  

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller   +14 more
wiley   +1 more source

Senior hospital registrars : from failure to success in examinations

open access: yes, 2006
There is intense pressure among senior hospital registrars who are on training programs to develop the skills and pass the final examination to become consultants.
Craven, Rhonda, Tremayne, Patsy
core  

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Advances in the conceptual understanding of students' goals and academic self-concept : a multidimensional and hierarchical approach

open access: yes, 2004
The purpose of this study is to examine the potential multidimensional and hierarchical structure of student’s motivational goals and academic self-concept (SC).
Dowson, Martin   +2 more
core  

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe   +7 more
wiley   +1 more source

How far can the big fish swim? Extending the reach of the big-fish-little-pond effect

open access: yes, 2006
Although the promotion of a positive academic self-concept is regarded as an important educational objective, research has consistently demonstrated that in academically selective settings, students have lower academic self-concepts than those students ...
Seaton, Marjorie   +2 more
core  

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Self-concepts of primary students with mild intellectual disabilities : issues of measurement and educational placement

open access: yes, 2000
The educational placement of students with mild intellectual disabilities remains controversial. Arguments for educational placement are often based upon the anticipated impact upon self-concept.
Tracey, Danielle K. (R13635)   +1 more
core  

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