Results 141 to 150 of about 8,479,484 (314)

Moving out : the impact of deinstitutionalisation on salient affective variables for people with mild intellectual disabilities

open access: yes, 2004
This study examined the affective functioning of people with mild intellectual disabilities through examining salient variables that impact of people with disabilities who have been deinstitutionalised. Its primary purpose was to extend previous research
Craven, Rhonda   +2 more
core  

The Process and Implications of Self-Stigma in Schizophrenia [PDF]

open access: yes, 2014
Despite increased understanding of the diagnosis and treatment of mental health disorders, misperceptions about these disorders persist, leading to stigma and discrimination toward those who live with them. For the purposes of this article, stigma refers

core  

The Origin of Consciousness and Beyond

open access: yesFrontiers in Psychology, 2014
Andrea Eugenio eCavanna   +1 more
doaj   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

The chicken or the egg? : exploring causal relations between motivational goals, self-concept and academic achievement

open access: yes, 2004
Educational psychologists have long been interested in relationships, particularly causal relationships, between psychological variables and academic achievement.
Dowson, Martin   +2 more
core  

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe   +7 more
wiley   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Self-concept

open access: yes, 2017
Adolescence is a time of significant physical and emotional change. One of the key themes of research into adolescence is how self-identity and social relationships change during this period and how parents, peers, and significant others influence the ...
Ashman, A (15502244), Ian Hay (14738767)
core  

A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi   +17 more
wiley   +1 more source

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