Results 31 to 40 of about 856,149 (315)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Self-esteem and quality of life in patients undergoing plastic surgery [PDF]

Revista Brasileira de Cirurgia Plástica
Introduction: Self-esteem is defined by the value people place on themselves. It is an evaluative component of self-knowledge. Plastic surgery has been an alternative for people to improve their vision of themselves, feeling more confident and satisfied ...
Helmano Fernandes Moreira, Olivia Andrea de Alencar Costa Bessa, Nayana Soares Moreira   +2 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Associations between Emotional Dysregulation, Repetitive Negative Thoughts, and a Sense of Self-Continuity with Post-Divorce Adjustment in Divorced Women [PDF]

Women’s Health Bulletin
Background: Divorce leads to personal, psychological, and social changes, necessitating an exploration of post-divorce adjustment. This study aimed to investigate the associations between emotional dysregulation, repetitive negative thoughts, and self ...
Mahdieh Hassanpour, Parisa Pourmohammad
doaj   +1 more source

The subjective concept of morbidity: its assessment and connection with the motivation for treatment in persons who underwent psychosis

Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева, 2020
Medication compliance and motivation for treatment, as adaptive- compensatory reactions of patients to the awareness of the fact of their own ill- being, are based on subjective perception of the disorder.
N. B. Lutova, M. Y. Sorokin, O. V. Makarevich, V. D. Wied   +3 more
doaj   +1 more source

School Based Multicomponent Intervention for Obese Children in Udupi District, South India – A Randomized Controlled Trial [PDF]

Journal of Clinical and Diagnostic Research, 2016
Introduction: Childhood obesity and overweight is a global epidemics and has been increasing in the developing countries. Childhood obesity is linked with increased mortality and morbidity independent of adult obesity.
Baby S Nayak, Vinod H Bhat
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Self concept and adolescents' representations of significant others' images of them [PDF]

Psihologija, 2008
The main idea for this research is based on the assumptions of social interactionism. Adolescents representations of how they parents and friends see them are examined on the sample of 499 adolescents (12/13 i 16/17 years).
Krstić Ksenija
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source