Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Self-regulated learning in higher education : identifying key component processes [PDF]
The concept of self-regulated learning is becoming increasingly relevant in the study of learning and academic achievement, especially in higher education, where quite distinctive demands are placed on students.
Cassidy, SF
core +3 more sources
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Mengembangkan Self Concept Siswa Melalui Model Pembelajaran Concept Attainment [PDF]
Dalam pembelajaran matematika, siswa masih kurang memiliki self concept yang positif. Salah satu model pembelajaran yang dapat diterapkan untuk mengembangkan self concept siswa adalah model concept attainment.
Sumartini, T. S. (Tina)
core
Impact of Quality of Life Education on Self-Concept among Type 2 Diabetes Patients [PDF]
Background: Type 2 diabetes mellitus is a chronic disease with severe late complications and a chronic illness such as diabetes has effect on self concept.
صفوی, محبوبه +2 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The dimensional comparison theory (DCT) is based on the internal/external frame of reference model (I/E model). The model focuses on the effects of external (e.g., “How good am I in math compared to my classmates?”) and internal, dimensional comparisons (
Jens Möller
doaj +1 more source
Auto/Biographical Work as Bildung [PDF]
Bildung is a concept central to auto/biography. It can best be translated as ‘educative self-formation’ and describes the importance of the life-narrative as a vehicle for self-discovery, self-understanding and self-development.
Chapman, Judith
core
How does threat affect different types of people? Investigating a relationship between Big-Five personality and self-concept, and how threat may affect a self-concept network [PDF]
In this exploratory project, we aim to draw connections between Big-5 personality, threat, and self-concept. In the experiment, participants first completed the Big-5 inventory of personality measuring openness, conscientiousness, extraversion ...
Connor, Kenneth
core

