Results 71 to 80 of about 4,150,068 (295)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

The Concept of "Self" and the "Other" in Western Movies [PDF]

open access: yes, 2001
Melodrama has been a part of the American life since colonial time. This genre, with its \u27hero-villain\u27 or \u27black and white\u27 development of characters, has formed the idea of the American heroes.
Basuki, R. (Ribut)
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Hidden attractors in fundamental problems and engineering models

open access: yes, 2015
Recently a concept of self-excited and hidden attractors was suggested: an attractor is called a self-excited attractor if its basin of attraction overlaps with neighborhood of an equilibrium, otherwise it is called a hidden attractor.
A Kuznetsov   +93 more
core   +1 more source

I Remember Me:Mnemonic Self-Reference Effects in Preschool Children [PDF]

open access: yes, 2011
It is well established that children recognize themselves in mirrors by the end of infancy, showing awareness of the self as an object in the environment. However, the cognitive impact of objective self-awareness requires further elucidation. This gap in
Anderson, James, R.   +2 more
core   +3 more sources

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

open access: yesFEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru   +6 more
wiley   +1 more source

Korean Version of the Confidence of Arm and Hand Movement Scale and Its Psychometric Properties [PDF]

open access: yesAnnals of Rehabilitation Medicine
Objective To investigate the impact of self-efficacy in using one’s upper limbs on the overall wellbeing of stroke patients, we developed the Korean version of the Confidence of Arm and Hand Movement (K-CAHM) scale by modifying the original CAHM to suit ...
Hanna Kim, Yeajin Ham, Joon-Ho Shin
doaj   +1 more source

Understanding community policing [PDF]

open access: yes, 2009
Purpose The purpose of the paper is to explore, in broad terms, how policing needs to be developed in communities today. Approach The approach is normative and analytical, considering the meaning of policing in general, and community policing in ...
Somerville, Peter
core   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Program Layanan Bimbingan Konsep Diri (Self Concept) Pada Siswa Tunalaras

open access: yesJurnal Pendidikan dan Kebudayaan, 2010
The purpose of this research is to find the guiding self-concept service program for unsociable children in SLB/E Surabaya. The result shows that: 1) was not still optimal yet to get guiding self-concept for developing aware of the importance the self ...
Achmad Sofyan Hanif, Sujarwanto --
doaj   +1 more source

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