Results 91 to 100 of about 8,191,393 (311)

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

open access: yesFEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai   +8 more
wiley   +1 more source

Self-concept enhancement : a meta-analysis integrating a multidimensional perspective

open access: yes, 2004
A meta-analysis was conducted to assess the impact of interventions designed to enhance self-concept for children and adolescents. The limitations of previous self-concept intervention meta-analyses were avoided by capitalising on advances in self ...
Craven, Rhonda   +2 more
core  

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

The role of academic self-concept and interest in determining academic achievement

open access: yes, 2004
Do positive self-perceptions lead to higher levels of achievement? If so, what is more important – self-concept or interest? In two large-scale, longitudinal German studies (Study 1: N = 5,649; Study 2: N = 2,264) we evaluate the reciprocal effects of ...
Lüdtke, Oliver   +4 more
core  

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

University students’ perceptions of their ‘ability selves’ and employability: a pilot study

open access: yesNordic Journal of Studies in Educational Policy, 2018
This study sets out to investigate the university students’ perceptions of their current and expected ‘ability selves’ and the contribution of such perceptions to students’ views of their own employability.
Hannu Räty   +4 more
doaj   +1 more source

Untangling the web : reports of self-concept, academic motivation and perceived discrimination for indigenous secondary students

open access: yes, 2006
Recently, a new direction has emerged within the field of educational psychology that has sought to address the inequities between Indigenous Australian students and the wider Australian student population.
Craven, Rhonda, Bodkin-Andrews, Gawaian
core  

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Helping the self help others: Self-affirmation increases self-compassion and pro-social behaviors

open access: yesFrontiers in Psychology, 2014
Reflecting on an important personal value in a self-affirmation activity has been shown to improve psychological functioning in a broad range of studies, but the underlying mechanisms for these self-affirmation effects are unknown.
Emily K Lindsay, J. David Creswell
doaj   +1 more source

Unmasking the true effects of self-concept interventions and suggested guidelines for rectification

open access: yes, 2004
Over recent decades, traditional literature reviews have intimated that self-concept interventions have produced inconsistent or disappointing results (e.g., Marsh & Craven, 1997).
Craven, Rhonda   +2 more
core  

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