Results 51 to 60 of about 854,283 (292)
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
First Impression Formation Based on Valenced Self-Disclosure in Social Media Profiles
This study aims to understand how the valence of self-disclosure (operationalized as the dominantly positive vs. balanced vs. dominantly negative social media posts of a future collaborator) influences first impression formation on social media.
Yuren Qin +3 more
doaj +1 more source
Adolescent Self-Disclosure and Loneliness: Private Self-Consciousness and Parental Influences [PDF]
Using structural equation techniques, we tested a theoretical model designed to describe the causal relations existing among loneliness, self-disclosure to peers and parents, and specific antecedent variables.
Davis, Mark H., Franzoi, Stephen L.
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Long-term home isolation has had a certain impact on adolescents' enthusiasm for interpersonal communication and desire for self-disclosure during COVID-19.
Li Chen, Rui Cheng, Bo Hu
doaj +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
The Essential Role of Securities Regulation [PDF]
This Article posits that the essential role of securities regulation is to create a competitive market for sophisticated professional investors and analysts (information traders).
Goshen, Zohar, Parchomovsky, Gideon
core +6 more sources
BackgroundNon-suicidal self-injury poses a serious threat to adolescents’ mental health, and if such behavior remains unexpressed or unshared over a long period, it may lead to further deterioration of their psychological well-being.
Zikang Liu +10 more
doaj +1 more source

