Results 71 to 80 of about 4,989,124 (282)
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Pilots and athletes: Different concerns, similar concussion non-disclosure.
PLoS ONE, 2019 ObjectivesConcussion non-disclosure research has focused almost exclusively on athletes. The focus on athletic populations has been sensible considering athletes' demonstrated susceptibility to sustaining and concealing concussions.
Craig A Foster +2 more
doaj +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
, 1980 The purpose of this study was to investigate the effect of Progressive Relaxation Training on self-reported self-disclosure and anticipated willingness to self-disclose in the future by male subjects.
Hotaling, Marjorie W.
core
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
, 2020 Supplemental Material, jm.19.0560-File003 for Full Disclosure: How Smartphones Enhance Consumer Self-Disclosure by Shiri Melumad and Robert Meyer in Journal of ...
Robert Meyer (804292) +1 more
core +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Journal of Theoretical and Applied Electronic Commerce ResearchMobile payment platforms not only streamline users’ financial transactions but also encourage their participation in investment activities and additional services.
Haiqin Xu, Jian Li
doaj +1 more source
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, EarlyView.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
Jurnal Ilmiah Bimbingan Konseling Undiksha, 2016 Penelitian ini bertujuan untuk mengetahui pengaruh model konseling rasional emotif teknik restrukturisasi kognitif dan teknik latihan asertif terhadap self disclosure siswa kelas VIII SMP Negeri 3 Singaraja.
Ni Komang Tria Hinduani . +2 more
doaj +1 more source