Results 51 to 60 of about 2,672,764 (289)
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
ObjectiveInterventions for emerging adults (EAs) with type 1 diabetes (T1D) focus on goal setting, but little is known about how goal achievement relates to intervention outcomes.
Cynthia A. Berg +8 more
doaj +1 more source
Facilitating self-regulation in higher education through self-report [PDF]
For the purpose of examining a tool to enable students in higher education to systematically reflect on their own self-regulation, a modified version of the Martinez-Pons Scale of Self-Regulation was used in a cohort study of 75 first-year undergraduate ...
Maclellan, Effie, Soden, Rebecca
core +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Regulatory and personality predictors of the reliability of professional actions [PDF]
Background. The present research is carried out in the context of the conscious self-regulation of professional activity. Objective. It investigates the regulatory and personality predictors of reliability in rescue operations under stressful ...
Morosanova V.I. +4 more
doaj +1 more source
Hubungan Self Regulation Dengan Self Determination (Studi Pada Mahasiswa Aktif Semester Genap 2013/2014, Ipk ≤ 2.75, Fakultas Psikologi, Universitas X, Jakarta) [PDF]
Students who are motivated towards their task, will be able to perform its task properly and independently, as well as having a high level of creativity in their work, so that students are expected to produce satisfactory academic achievement.
Rozali, Y. A. (Yuli)
core
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
The educational landscape is evolving rapidly due to the technological transformations brought by the digital age, necessitating innovative approaches to engage Generation Z learners.
Sarah Chardonnens
doaj +1 more source
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Background: The purpose of this study is to examine and determine the design and content elements of health app that facilitate usage from user perception.
Shivangi Vaishnav +2 more
doaj +1 more source

