Results 51 to 60 of about 3,034 (283)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Ecosphere, 2019 The pollination syndromes have been widely used to predict effective pollinators of plant species and provide the mechanistic explanation of floral diversity.
Babu Ram Paudel +4 more
doaj +1 more source
Rubber tree clonal plantations: Grafted vs self-rooted plant material [PDF]
, 2017 The forest tree species Hevea brasiliensis is extensively planted in the humid tropics to meet the increasing demand for natural rubber. Huge quantities of planting stock are therefore needed.
Masson, Aurélien, Monteuuis, Olivier
core +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
PLoS Genetics, 2019 Allopolyploidy has played a major role in plant evolution but its impact on genome diversity and expression patterns remains to be understood. Some studies found important genomic and transcriptomic changes in allopolyploids, whereas others detected a ...
Dmytro Kryvokhyzha +6 more
doaj +1 more source
Embodiment, Lived Experience and Anorexia: The Contribution of Phenomenology to a Critical Therapeutic Approach [PDF]
, 2001 En este articulo nos proponemos recuperar el trabajo de Merlau-Ponty como un instrumento válido para la elaboración de una psicología crítica ya sea en como referente teórico o en sus aplicaciones prácticas.
Burkitt, Ian, Sanz Porras, Jordi
core +4 more sources
Frailty Exacerbates Disability in Progressive Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background To evaluate frailty in severe progressive multiple sclerosis (PMS) and to investigate the underlying mechanisms. Methods This prospective, cross‐sectional, multicenter study enrolled a late severe PMS group requiring skilled nursing (n = 53) and an age, sex, and disease duration‐matched control PMS group (n = 53).
Taylor R. Wicks +10 more
wiley +1 more source
Postglacial colonization and parallel evolution of metal tolerance in the polyploid Cerastium alpinum [PDF]
, 2005 The Fennoscandian flora is characterized by a high frequency of polyploids, probably because they were more successful than diploid plants in colonizing after the last Ice Age.
Nyberg Berglund, Anna-Britt
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Myasthenia gravis (MG) is a rare disorder characterized by fluctuating muscle weakness with potential life‐threatening crises. Timely interventions may be delayed by limited access to care and fragmented documentation. Our objective was to develop predictive algorithms for MG deterioration using multimodal telemedicine data ...
Maike Stein +7 more
wiley +1 more source
PlantsResearch on Satyrium nepalense var. ciliatum (Lindl.) Hook. f. has primarily focused on populations in Northwestern Yunnan, with limited studies on pollination syndromes and insect behavior.
Lei Tao +6 more
doaj +1 more source