Results 91 to 100 of about 2,243,617 (302)
MiR‐513a promotes human erythroid differentiation by modulating c‐Jun
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim +11 more
wiley +1 more source
Ciência Sem Fronteiras na UFSC: A Mobilidade Estudantil Em Perspectiva Sociológica [PDF]
TCC (graduação) - Universidade Federal de Santa Catarina, Centro de Filosofia e Ciências Humanas, Curso de Ciências Sociais.O presente trabalho tem como objeto de estudo o Programa Ciência Sem Fronteiras – CsF – e sua implementação na Universidade ...
Martinez, Karen Lucia
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Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
teste sem mod secutityteste sem mod secutityteste sem mod secutityteste sem mod secutityteste sem mod secutityteste sem mod secutityteste sem mod secutityteste sem mod ...
teste sem mod secutity, teste sem mod secutity
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YIPFα1A expression is regulated by multilayered molecular mechanisms
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Simulating the long term effect of asset management strategies on reliability of supply
This paper presents long-term power system reliability prognosis methods aimed for decision support in asset management and grid development. The prognosis method combines power system reliability assessment with simulation of the time development of ...
Ivar Bjerkebæk +3 more
doaj +1 more source
A desenvoltura é a expressão de uma denegação em face dos valores aos quais se recusa reconhecer a importância. É, então, uma noção essencial para pensar a arte contemporânea, pois reporta-se a um comportamento que questiona a autoridade. Nesta ótica, tento analisar aqui as conseqüências da atitude irônica de certos artistas modernos e pós-modernos ...
openaire +2 more sources
Paraugu sagatavošana SEM dažādu materiālu virsmas pētījumiem
Darbs veltīts dažādu materiālu paraugu sagatavošanas metodikas izstrādei skenējošās elektronu mikroskopijas ( SEM ) pētījumiem uz lauka emisijas skenējošā elektronu mikroskopa Mira/LMU ( Tescan, Čehija ).
Ruģele, Kristīne +5 more
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