Results 91 to 100 of about 2,717,459 (291)

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Ei sørsamisk katastrofe i norsk minnekultur

open access: yesTidsskrift for Kulturforskning
In 1948, a bus carrying a South Saami delegation to a national indigenous convention crashed, killing 16 of the delegates. Although being one of largest in Norwegian history, the accident is very little known, even disregarded, in national public ...
Leiv Sem
doaj   +1 more source

SEM-EDS analysis of particles.

open access: yes, 2019
The SEM images and EDS elemental data for particles observed in the printed FDA PLA extracts. A polymer-derived particle is shown in (A.), as indicated by the C signal in the EDS spectrum.
Joel D. Rindelaub (1422097)   +3 more
core   +1 more source

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

open access: yesMolecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both   +7 more
wiley   +1 more source

Les SEM en 2015...

open access: yes, 2006
16 pages, figuresLa Fédération des Sem a souhaité lors de son congrès annuel des 10, 11 et 12 octobre 2006, qui marquera la quatre-vingtième année de la naissance de ce mouvement en France, mettre l'accent sur son histoire et sur l'exploitation des ...
Godet, Michel
core  

Elaboração da contabilidade: um levantamento das dificuldades encontradas em entidades sem fins lucrativos [PDF]

open access: yes, 2009
TCC (Graduação) - Universidade Federal de Santa Catarina. Centro Socioeconômico. Curso de Ciências ContábeisEste trabalho teve como objetivo levantar junto às entidades sem fins lucrativos, as dificuldades encontradas para elaborar a sua contabilidade e ...
Gonçalves, Álvaro Elias
core  

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

SEM pseudonyme de Georges Goursat (illustrateur 1863-1934) : signature dédicacée “A Mayol”

open access: yes, 1911
SEM pseudonyme de Georges Goursat (illustrateur 1863-1934) : signature dédicacée “A Mayol” (1911). [médihal mot-clé SEM pseudonyme de Georges Goursat (illustrateur 1863-1934)
Daphy, Éliane, SEM (illustrateur), .
core  

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

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