Results 21 to 30 of about 1,143,253 (247)
Following the introduction of Buddhism to China, various strategies of accommodation with Chinese culture were developed, all amounting to some form of syncretism with Chinese religions, mainly Confucianism. Buddhism in pre-modern Korea displayed similar
Sem Vermeersch
doaj +1 more source
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma+8 more
wiley +1 more source
Potential of Thermal Energy Storage for a District Heating System Utilizing Industrial Waste Heat
The potential for utilizing industrial waste heat for district heating is enormous. There is, however, often a temporal mismatch between the waste heat availability and the heating demand, and typically fossil-based peak boilers are used to cover the ...
Hanne Kauko+3 more
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The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti+3 more
wiley +1 more source
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink+6 more
wiley +1 more source
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale+9 more
wiley +1 more source
Om framstillinga av sørsamar i Trøndelags historie
On the depiction of the South Saami people in Trøndelags historie The 2005 publication of a three-volume history of the Trøndelag region ignited a heated debate.
Leiv Sem
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The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu+3 more
wiley +1 more source