Reaching an ACCORD on Glycemia and Systolic Blood Pressure Targets in Type 2 Diabetes Mellitus [PDF]
, 2018 MacDonald, Thomas M., Mackenzie, Isla S.
core +2 more sources
Seizure recurrence after GLP‐1 receptor agonist initiation in adults with epilepsy
Epilepsia, EarlyView.Abstract Objective To examine whether initiation of glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) is associated with seizure recurrence and related outcomes in adults with epilepsy and type 2 diabetes. Methods We conducted a retrospective cohort study using de‐identified electronic health records from the TriNetX Research Network (January 2003 ...
Majd A. AbuAlrob +5 more
wiley +1 more source
Artificial lipidation of proteins and peptides: from mechanism to clinical applications
The FEBS Journal, EarlyView.Artificial lipidation transforms protein and peptide therapeutics by attaching fatty acid chains through reversible or permanent chemical strategies. This biomimetic approach delivers four key therapeutic advantages: extended circulation times (enabling weekly instead of daily dosing), alternative administration routes including oral delivery, precise ...
Jiaming Mu, Emily Vong, Sheiliza Carmali
wiley +1 more source
Ozempic (semaglutide) versus Nonpharmacologic Interventions For Weight Management in Overweight Individuals [PDF]
Ozempic (semaglutide) is a medication prescribed for individuals managing Type 2 Diabetes Mellitus by mimicking the action of a hormone called GLP-1, helping to regulate glucose levels by stimulating insulin secretion and reducing glucagon secretion ...
DiGirolamo, Emma +4 more
core +1 more source
Journal of Diabetes Investigation, EarlyView.This retrospective study compared oral semaglutide and SGLT2 inhibitors in patients with type 2 diabetes over 6 months. Both treatments significantly reduced HbA1c, body weight, and fat mass. Although the reduction in fat mass was comparable, changes in skeletal muscle mass tended to be less favorable with SGLT2 inhibitors than with oral semaglutide ...
Yasuhiro Omori +6 more
wiley +1 more source
Incretin Analogues for Weight Reduction in Non-Diabetic Obese: A Review of Liraglutide, Semaglutide, and Tirzepatide Beyond Glycemic Control. [PDF]
Rambam Maimonides Med JBonga KN, Padhan M.
europepmc +1 more source
Impact of weight‐loss interventions on psoriasis severity: A systematic review and meta‐analysis
Journal of the European Academy of Dermatology and Venereology, EarlyView.Weight‐loss interventions were associated with clinically and statistically significant improvements in psoriasis severity (PASI and PASI 75) and quality of life (DLQI). These findings support the role of weight‐loss interventions as effective adjuncts to medical therapy and their integration into holistic psoriasis care.
Sarah Morrow +6 more
wiley +1 more source
Erratum. Gradual Titration of Semaglutide Results in Better Treatment Adherence and Fewer Adverse Events: A Randomized Controlled Open-Label Pilot Study Examining a 16-Week Flexible Titration Regimen Versus Label-Recommended 8-Week Semaglutide Titration Regimen Diabetes Care 2025;48:1607-1611. [PDF]
Diabetes CareEldor R +7 more
europepmc +1 more source
Journal of Internal Medicine, EarlyView.Abstract Increased urinary albumin excretion is a strong predictor for cardiovascular events in persons with and without decreased glomerular filtration rate and can be assessed with the urinary albumin‐to‐creatinine ratio (UACR), which is a selective, sensitive, and convenient method for patients.
Holly J. Kramer, George L. Bakris
wiley +1 more source
Generation and characterisation of a humanised GLP-1 receptor mouse model for translational drug development. [PDF]
EBioMedicineSonne N +15 more
europepmc +1 more source