Results 161 to 170 of about 20,052 (248)

Pre‐Treatment Concerns and Their Association With Functioning and Well‐Being During Incretin‐Based Therapy: A Cross‐Sectional Study

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aim This study aims to examine weight‐loss history and pre‐treatment concerns, and their associations with current functioning and well‐being in adults undergoing incretin‐based pharmacotherapy for obesity. Materials and Methods This cross‐sectional study analysed 411 adults treated with three different incretin‐based medications. Demographics,
Ali Kapan   +4 more
wiley   +1 more source

Complementary neuroprotective effects of semaglutide and papaya in diabetic encephalopathy via antioxidant and insulin-signaling pathways. [PDF]

open access: yesSci Rep
Zeweil MM   +11 more
europepmc   +1 more source

GLP‐1 Receptor Agonists in Brazil: Landscape of Consumption, Safety and Regulation

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Background The escalating use of Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) is reshaping pharmaceutical consumption patterns and posing unprecedented challenges to healthcare systems worldwide. This study analyzes the landscape of GLP‐1 RA consumption, safety monitoring and regulatory oversight in Brazil.
Renato Lopes Hurtado   +3 more
wiley   +1 more source

Dose‐Escalation Regimens for Incretin Mimetics in Type 2 Diabetes Are Associated With Tolerance for Nausea and Vomiting

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims/Hypothesis Initial dose‐escalation has been shown to mitigate gastrointestinal adverse events in people treated with incretin‐based medications. We aimed to analyse dose‐response relationships for the proportion of study participants reporting nausea and vomiting among those exposed to incretin mimetics approved for Type 2 diabetes (GLP‐1
Michael A. Nauck   +3 more
wiley   +1 more source

Clinical Pharmacokinetics of Semaglutide: A Systematic Review

open access: yesDrug Design, Development and Therapy
Xi-Ding Yang,1,2 Yong-Yu Yang1,3 1Department of Pharmacy, The Second Xiangya Hospital of Central South University, Changsha, Hunan, People’s Republic of China; 2Phase I Clinical Trial Center, The Second Xiangya Hospital of Central South University ...
Yang XD, Yang YY
doaj  

Semaglutide promotes bone marrow-derived progenitor cell flux towards an anti-inflammatory and pro-regenerative profile in high-risk patients: the SEMA-VR CardioLink-15 trial. [PDF]

open access: yesEur Heart J
Park B   +16 more
europepmc   +1 more source

Weight Loss as a Determinant of Histological Improvement in Metabolic Dysfunction‐Associated Steatotic Liver Disease in People With Obesity. A Systematic Review and Network Meta‐Analysis of Randomised Clinical Trials

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Background Metabolic dysfunction‐associated steatotic liver disease (MASLD) is closely linked to obesity and insulin resistance, and sustained weight loss is associated with histological improvement. Whether different obesity‐management modalities exert weight‐independent hepatic effects remains uncertain.
Matteo Monami   +11 more
wiley   +1 more source

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