Results 31 to 40 of about 19,015 (246)

The Effectiveness of GLP-1 Receptor Agonist Semaglutide on Body Composition in Elderly Obese Diabetic Patients: A Pilot Study

open access: yesMedicines, 2022
Background and Objectives: This study aimed to investigate the changes in obesity severity, glucose metabolism, and body composition in patients with obesity and type 2 diabetes mellitus treated with glucagon-like peptide 1 receptor agonist (GLP1-RA ...
Yoshinori Ozeki   +7 more
doaj   +1 more source

Efficacy of Semaglutide in a Subcutaneous and an Oral Formulation

open access: yesFrontiers in Endocrinology, 2021
Despite the benefits of early and effective glycemic control in the management of type 2 diabetes (T2D), achieving glycated hemoglobin (HbA1c) targets is challenging in some patients. Glucagon-like peptide-1 receptor agonists (GLP-1RAs) provide effective
Juris J. Meier
doaj   +1 more source

Oral diabetes medication monotherapy and short-term mortality in individuals with type 2 diabetes and coronary artery disease [PDF]

open access: yes, 2018
Objective To determine whether sulfonylurea use, compared with non-sulfonylurea oral diabetes medication use, was associated with 2-year mortality in individuals with well-controlled diabetes and coronary artery disease (CAD). Research design and methods
Berkowitz, Seth A   +7 more
core   +3 more sources

The cardiovascular safety of incretin-based therapies: a review of the evidence [PDF]

open access: yes, 2013
Cardiovascular disease (CVD) is a leading cause of morbidity and mortality in people with diabetes and therefore managing cardiovascular (CV) risk is a critical component of diabetes care. As incretin-based therapies are effective recent additions to the
Petrie, J.R.
core   +2 more sources

Cardiovascular disease prevalence and risk factor prevalence in Type 2 diabetes:a contemporary analysis [PDF]

open access: yes, 2018
Aims: To describe the prevalence of major cardiovascular disease (CVD) and risk factor control in a contemporary population with Type 2 diabetes.Methods: We used data from the national registry in Scotland, Scottish Care Information-Diabetes, linked to ...
Blackbourn, L. A. K.   +7 more
core   +4 more sources

Incident ischaemic stroke and Type 2 diabetes:trends in incidence and case fatality in Scotland 2004-2013 [PDF]

open access: yes, 2017
Aim: To describe trends in first ischaemic stroke incidence and case fatality in adults with and without a diagnosis of Type 2 diabetes prior to their ischaemic stroke event in Scotland between 2004 and 2013.
Anwar   +27 more
core   +3 more sources

Semaglutide [PDF]

open access: yesReactions Weekly, 2022
Agostino Milluzzo, Laura Sciacca
  +5 more sources

The maintenance of long-term weight loss after semaglutide withdrawal in obese women with PCOS treated with metformin: a 2-year observational study

open access: yesFrontiers in Endocrinology
BackgroundWithdrawal of semaglutide is frequently followed by weight regain due to compensatory biological changes that prevent the maintenance of long-term weight loss. There are some studies implying that metformin might attenuate weight regain.
Mojca Jensterle   +5 more
doaj   +1 more source

Glucagon-Like Peptide-1 Receptor Agonist Semaglutide Improves Eating Behavior and Glycemic Control in Japanese Obese Type 2 Diabetic Patients

open access: yesMetabolites, 2022
We evaluated time-course changes and the relationship between eating behavior and glycemic profile during the treatment of 34 obese type 2 diabetic patients with the glucagon-like peptide-1 receptor agonist (GLP1-RA) semaglutide.
Takayuki Masaki   +6 more
doaj   +1 more source

Effects of once-weekly semaglutide on appetite, energy intake, control of eating, food preference and body weight in subjects with obesity.

open access: yes, 2017
AIM: To investigate the mechanism of action for body weight loss with semaglutide. MATERIALS AND METHODS: This randomised, double-blind, placebo-controlled, two-period crossover trial investigated the effects of 12 weeks treatment with once-weekly ...
Axelsen, MB   +6 more
core   +1 more source

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