Results 71 to 80 of about 24,321 (248)

Decoding Spatial Heterogeneity and Multi‐Omics Regulation with Hierarchical Graph Learning

Advanced Science, EarlyView.
ABSTRACT Recent advances in spatial multi‐omics technologies have enabled the simultaneous profiling of multiple molecular layers within the same tissue slice, providing unprecedented opportunities to investigate tissue spatial organization. However, most existing computational methods identify spatial domains in a purely data‐driven manner, rarely ...
Jiazhou Chen, Jiahui Xie, Yi Liao, Junyu Li, Longqi Liu, Xin Gao, Hongmin Cai   +6 more
wiley   +1 more source

Transdiagnostic Analysis of Verbal Fluency across Autism Spectrum Disorder, Schizophrenia, and Neurotypical Healthy Control Groups

European Psychiatry
Introduction Verbal fluency, a cognitive function that reflects executive functions and the rapid retrieval of pertinent information from memory, has yielded inconsistent findings in previous research on autism spectrum disorder (ASD), however in ...
F. Kinga, E. J. Zarka, O. Pesthy
doaj   +1 more source

Global and Specific Profiles of Executive Functioning in Prodromal and Early Psychosis

Frontiers in Psychiatry, 2019
Objective: Numerous reports on neurocognitive functioning deficits in individuals at clinical high risk (CHR) and first-episode psychosis (FEP) patients suggest particular deficits in executive functioning (EF). However, to date, most of the studies have
Wu Jeong Hwang, Tae Young Lee, Won-Gyo Shin, Minah Kim, Minah Kim, Jihyang Kim, Junhee Lee, Junhee Lee, Jun Soo Kwon, Jun Soo Kwon, Jun Soo Kwon, Jun Soo Kwon   +11 more
doaj   +1 more source

How Advanced Artificial Intelligence Technologies Shape Drug–Drug and Drug–Target Interaction Modeling

Advanced Science, EarlyView.
This review explores the convergence of artificial intelligence technologies in modeling drug–drug and drug–target interactions. By evaluating advanced feature engineering, architectural innovations, and learning paradigms reveals shared evolutionary trends and critical challenges, such as cold‐start settings and shortcut learning.
Xin Sun, Tong Wang
wiley   +1 more source

stMixer for Scalable Mosaic Integration and Label Transfer in Spatial Histology and Multi‐Omics

Advanced Science, EarlyView.
stMixer is an unsupervised framework for scalable integration and label transfer across spatial histology and multi‐slide multi‐omics data with incomplete modality overlap. It combines self‐looped cross‐attention, multimodal metric learning, and graph‐guided cluster voting to align heterogeneous sections, correct batch effects, and propagate ...
Qixing Yang, Yan Wang, Luonan Chen, Chunman Zuo   +3 more
wiley   +1 more source

De Novo Design of Membrane‐Targeting Antimicrobial Peptides Against Gram‐Negative Bacteria Using a Generative Artificial Intelligence Framework

Advanced Science, EarlyView.
Antimicrobial resistance caused by Gram‐negative bacteria remains difficult to overcome due to the protective outer membrane. To address this challenge, a multi‐condition constrained generative AI framework, GenMTAMP is proposed for de novo membrane‐targeting antimicrobial peptide design by integrating physicochemical and spatial structure descriptors.
Jingxiao Yu, Da‐Wen Sun, QingYi Wei, Yibing Zhang, Jidong Tang, Hongbin Pu   +5 more
wiley   +1 more source

ProSiteHunter: A Unified Framework for Sequence‐Based Prediction of Protein‐Nucleic Acid and Protein‐Protein Binding Sites

Advanced Science, EarlyView.
This study proposed a unified sequence‐based framework for protein binding site prediction, which adopted a tri‐track semantic multi‐source feature fusion strategy to effectively capture diverse macromolecular interaction sites and further improved the accuracy of antibody‐antigen interaction prediction.
Dongliang Hou, Qihang Zhen, Zexin Lv, Xinyue Cui, Suhui Wang, Minghua Hou, Zhan Zhou, Xiaogen Zhou, Guijun Zhang   +8 more
wiley   +1 more source

Correlation of INECO Frontal Screening With Verbal Fluency Tasks and MMSE in Persian Healthy Population

Journal of Modern Rehabilitation, 2018
Introduction: INECO Frontal Screening (IFS) is a brief sensitive screening tool able to detect executive dysfunctions. IFS-P is the Persian version of IFS.
Fatemeh Satarian, Azar Mehri, Shohreh Jalaie   +2 more
doaj  

Investigating the cognitive architecture of verbal fluency: evidence from an interference design on 487 controls

Frontiers in Psychology
IntroductionNumerous studies have explored the linguistic and executive processes underlying verbal fluency using association designs, which provide limited evidence.
Flore Dorchies, Flore Dorchies, Camille Muchembled, Corinne Adamkiewicz, Olivier Godefroy, Olivier Godefroy, Martine Roussel, Martine Roussel   +7 more
doaj   +1 more source

Executive Processes Underpin the Bilingual Advantage on Phonemic Fluency: Evidence From Analyses of Switching and Clustering

Frontiers in Psychology, 2019
Bilinguals often show a disadvantage in lexical access on verbal fluency tasks wherein the criteria require the production of words from semantic categories.
John E. Marsh, John E. Marsh, Patrik Hansson, Daniel Eriksson Sörman, Jessica Körning Ljungberg, Jessica Körning Ljungberg   +5 more
doaj   +1 more source