Results 151 to 160 of about 47,177 (295)
Advanced Science, EarlyView.SMarT‐Diff introduces a multi‐objective generative paradigm that integrates scaffold hopping with structure‐aware scoring to enable controlled exploration beyond the training distribution. The framework consistently balances drug‐likeness, synthesizes accessibility and bioactivity, yielding chemically diverse candidates with enhanced properties.
Yuwei Yang +8 more
wiley +1 more source
Spatio Concept relation accompanied interface to bridge semantic gap of video search and retrieval
, 2015 Video search and retrieval becoming hot topic in multimedia information retrieval. However, the ‘semantic gap’ still persists and urges effective mechanisms to bridge the gap.
Abdullah, NA +2 more
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Advanced Science, EarlyView.MarginPath is a novel vision‐language system that automates breast cancer margin assessment using a single label‐free multiphoton microscopy image. By integrating tumor‐associated collagen signatures with virtual H&E imaging, it generates accurate margin heatmaps and comprehensive diagnostic reports.
Shu Wang +15 more
wiley +1 more source
Image Semantic Retrieval Challenges and Thesauri Modern Applications
Iranian Journal of Information Processing & Management, 2012 Today, images are used in almost every career, and a different range of professional groups use images in their work. They have always been used as a means to convey information.
Farahnaz sadoughi +4 more
doaj
Advanced Science, EarlyView.A biomimetic artificial intelligence system, PancDS, has been developed to distinguish pancreatic ductal adenocarcinoma from mass‐forming pancreatitis by adaptively integrating clinical data, radiomics, and deep learning features. Validated across multicenter, reader‐study, and prospective settings, PancDS improves diagnostic accuracy, particularly for
Zhibo Wang +13 more
wiley +1 more source
PlantGFM: A Genomic Foundation Model for Discovery and Creation of Plant Genes
Advanced Science, EarlyView.A plant genomic foundation model pre‐trained on 12 species enables both accurate gene prediction and de novo gene design. Through AI‐human knowledge screening, seven designed sequences showed transcriptional activity in plants, with two expressing stable proteins—demonstrating the first DNA‐RNA‐protein expression of LLM‐generated genes in plants and ...
Changhao Li +10 more
wiley +1 more source
Advanced Science, EarlyView.This review explores the convergence of artificial intelligence technologies in modeling drug–drug and drug–target interactions. By evaluating advanced feature engineering, architectural innovations, and learning paradigms reveals shared evolutionary trends and critical challenges, such as cold‐start settings and shortcut learning.
Xin Sun, Tong Wang
wiley +1 more source
Advanced Science, EarlyView.PhosSight is a unified deep‐learning framework for phosphoproteome identification, featured by a phosphorylation‐aware detectability predictor. It improves identification sensitivity in DDA through deep re‐localization and rescoring, accelerates DIA searches by detectability‐guided spectral library pruning, and expands phosphoproteome coverage to ...
Ben Wang +10 more
wiley +1 more source
Beyond the Semantic Gap: A Revolutionary Response to the Deepest Objections Against Consciousness Theories [PDF]
The most profound objections to consciousness theories—including Processual Experiential Realism—center on three fundamental challenges: the persistence of the semantic gap between physical and phenomenal concepts, the empirical inaccessibility of ...
Tan, Kwan Hong
core +1 more source
On bridging the semantic gap in knowledge-based question answering
, 2016 A knowledge-based question answering (KB-QA) system is one that answers natural language questions with information stored in a large-scale knowledge base (KB). The classical KB-QA approach involves two steps: semantic parsing and query execution. First,
Yin, Pengcheng, 殷鵬程
core