Results 91 to 100 of about 55,127 (292)
Advanced Science, EarlyView.SMarT‐Diff introduces a multi‐objective generative paradigm that integrates scaffold hopping with structure‐aware scoring to enable controlled exploration beyond the training distribution. The framework consistently balances drug‐likeness, synthesizes accessibility and bioactivity, yielding chemically diverse candidates with enhanced properties.
Yuwei Yang +8 more
wiley +1 more source
Advanced Science, EarlyView.PhosSight is a unified deep‐learning framework for phosphoproteome identification, featured by a phosphorylation‐aware detectability predictor. It improves identification sensitivity in DDA through deep re‐localization and rescoring, accelerates DIA searches by detectability‐guided spectral library pruning, and expands phosphoproteome coverage to ...
Ben Wang +10 more
wiley +1 more source
Semantic theories of information
Ciência da Informação, 1977 Ao final dos anos 40, todas as teorias matemáticas da informação sugerem conceitos antagônicos de informação, além de parecerem deixar de lado a noção de significado. A análise de Shannon sobre a quantidade de informação contida em um sinal declina explicitamente de qualquer interesse pelo significado,sendo qualificada pelos semanticistas de inadequada.
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About the nature of Kansei information, from abstract to concrete [PDF]
, 2014 Designer’s expertise refers to the scientific fields of emotional design and kansei information. This paper aims to answer to a scientific major issue which is, how to formalize designer’s knowledge, rules, skills into kansei information systems.
ESQUIVEL, Daniel +2 more
core
Advanced Science, EarlyView.This study proposed a unified sequence‐based framework for protein binding site prediction, which adopted a tri‐track semantic multi‐source feature fusion strategy to effectively capture diverse macromolecular interaction sites and further improved the accuracy of antibody‐antigen interaction prediction.
Dongliang Hou +8 more
wiley +1 more source
Interpretting Information Based on Quantum Theory of Physics (Quantum Theory of Information)
Iranian Journal of Information Processing & Management, 2014 There are different theories on information as Shannon's Information or Communication Theory, Semantic Theory of Information, Cybernetics Theory, Quantum Theory of Information and Quantum Information Theory, each one viewing information from a different ...
Mitra pashootanizadeh, Mortaza kokabi
doaj
Advanced Science, EarlyView.This study introduces a foundation model‐based biomarker for risk stratification of pathological response in non‐small cell lung cancer. A Vision Mamba super‐resolution model standardizes heterogeneous CT images. A multi‐task Swin Transformer then fine‐tunes a pre‐trained lung foundation model to jointly optimize tumor segmentation and response ...
Yanglan Xu +10 more
wiley +1 more source
Advanced Science, EarlyView.Human neutrophils exist as two epigenetically imprinted subtypes defined by stable CD177 expression or absence — a ratio that persists across time, circadian rhythms, and inflammation. CD177− neutrophils display a distinct molecular landscape enriched in arginase 1 and lipid metabolism markers, accumulate in head‐and‐neck tumors, and associate with ...
Marcel Jung +39 more
wiley +1 more source
Towards a Measure Theory of Semantic Information
The classic account of the quantification of semantic information is that of Bar Hillel and Carnap. However, their approach assigns the maximum informativeness to a contradiction. This situation is what Floridi refers to as the Bar Hillel-Carnap paradox, and he developed a novel theory designed to remove this paradox.
openaire +2 more sources
, 2006 In the context of the Semantic Web, many ontology-related operations, e.g. ontology ranking, segmentation, alignment, articulation, reuse, evaluation, can be boiled down to one fundamental operation: computing the similarity and?or dissimilarity among ...
Harith Alani +12 more
core +1 more source