Results 111 to 120 of about 23,134,952 (376)

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

TYPES OF PATHOZOOSPERMIA IN MEN WITH INFERTILITY IN MARRIAGE АND/OR DISORDERS OF REPRODUCTIVE SYSTEM

open access: yesАндрология и генитальная хирургия, 2017
We analyzed 755 semen samples from men with infertility in marriage and/or disorders of reproductive system. Standard semen analysis (WHO, 2010) was performed for all the samples. Only 11 % of the samples were normozoospermic.
M. V. Andreeva   +9 more
doaj   +1 more source

Decline in human sperm counts during the past 50 years? [PDF]

open access: yes, 2005
There is widespread concern that environmental pollutants acting as xenoestrogens may affect human fertility adversely. Whether this has already made an impact on human fertility worldwide remains debatable at the present stage.
Jayachandra, Srinivasa   +2 more
core  

Psychological and physiological adaptations to sperm competition in humans [PDF]

open access: yes, 2005
Postcopulatory competition between males, in the form of sperm competition, is a widespread phenomenon in many animal species. The extent to which sperm competition has been an important selective pressure during human evolution remains controversial ...
Goetz, AT, Pound, N, Shackelford, TK
core   +2 more sources

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

A Research Documentation On Men's Sexual Health Disclosed [PDF]

open access: yes, 2010
When VigRX Plus was surveyed by Vedic Life-Sciences in proved to be the best pill treatment for sexual health.

core  

Sperm chromatin dispersion test before sperm preparation is predictive of clinical pregnancy in cases of unexplained infertility treated with intrauterine insemination and induction with clomiphene citrate [PDF]

open access: yes, 2016
Background/aims: A large proportion of men with normal sperm results as analyzed using conventional techniques have fragmented DNA in their spermatozoa.
De Croo, Ilse   +4 more
core   +2 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Zika virus preferentially replicates in the female reproductive tract after vaginal inoculation of rhesus macaques. [PDF]

open access: yes, 2017
Zika virus (ZIKV) is a mosquito-transmitted virus that can cause severe defects in an infected fetus. ZIKV is also transmitted by sexual contact, although the relative importance of sexual transmission is unclear.
Busch, Michael   +11 more
core   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

open access: yesFEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee   +3 more
wiley   +1 more source

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