Results 101 to 110 of about 15,364,011 (346)

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Correlation Analysis of Sperm Cryopreservation Quality with Serum Testosterone and Sperm gDNA Methylation Levels in Xiaoshan Chickens

open access: yesAnimals
Chicken semen cryopreservation is crucial for utilizing high-quality cockerel genetics, but semen is highly sensitive to cryoinjury, leading to poor preservation outcomes. This study aimed to establish a theoretical foundation for selecting cockerels for
Xue Du   +7 more
doaj   +1 more source

EXPRESSION OF GLYCOPROTEIN gD AND EVALUATION OF IMMUNE RESPONSE OF BOVINE HERPES VIRUS TYPE-1 IN BUFFALO [PDF]

open access: yesExploratory Animal and Medical Research, 2012
Bovine Herpes Virus type-1 (BoHV-1) causes a multitude of clinical symptoms in cattle, buffaloes and small ruminants. No effective live attenuated or killed vaccine is currently available and extensive research work in progress towards the development of
Sumit Chowdhury   +2 more
doaj  

Determination of the semen quality in male partners of infertile couples in Aminu Kano Teaching Hospital, Kano: A three year review

open access: yesIbom Medical Journal, 2011
Context Male infertility contributes a lot to the causes of infertility among couples attending Gynaecology clinics in our environment. Objectives: To determine semen quality in male partners of infertile couples attending Gynaecology Clinic in Aminu
Ibrahim SA, Muhammad Z
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

The Quality of Frozen Semen Sexing with Percoll Medium and Bovine Serum Albumin (BSA) in Dorper Sheep and Saanen Goat [PDF]

open access: yesE3S Web of Conferences
The study aimed to determine the quality of frozen semen sexing with percoll medium and Bovine Serum Albumin (BSA) in Dorper sheep and Saanen goats. The research was designed based on the experimental method, as the main plot is livestock (M) consisting ...
Sumaryadi Mas Y.   +5 more
doaj   +1 more source

The influence of omega‐3 fatty acids on semen quality markers: a systematic PRISMA review

open access: yesAndrology, 2019
Infertility affects about 15% of all couples worldwide. Male factors such as decreased semen quality contribute to around 40% of the cases. Recent reviews have shown that different foods and nutrients may improve semen quality.
A-M L Falsig, C. S. Gleerup, U. Knudsen
semanticscholar   +1 more source

Anonymous Semen Donation:Medical Treatment or Medical Kinship? [PDF]

open access: yes, 2013
Opinion in European countries has been divided over whether people conceived with donated gametes (semen, eggs and embryos) should be able to obtain identifying information about their genetic (donor) parents.
Speirs, Jennifer
core  

Male reproductive hormones and semen quality

open access: yesAsian Pacific Journal of Reproduction, 2019
Male reproductive functions are mediated by different hormones whose orchestrations remain a major research interest. The ‘master’ regulator hormonal axis is the hypothalamo- pituitary-gonadal/testicular axis which is led by the pulsatile release of ...
S. Dutta, P. Sengupta, S. Muhamad
semanticscholar   +1 more source

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