Results 91 to 100 of about 2,352,460 (337)

Semi-Numerical Simulation of Reionization with Semi-Analytical Modeling of Galaxy Formation

open access: yes, 2012
In a semi-numerical model of reionization, the evolution of ionization fraction is simulated approximately by the ionizing photon to baryon ratio criterion.
Chen, Xuelei   +5 more
core   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

open access: yesFEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Cross-plane heat conduction in thin solid films [PDF]

open access: yes, 2014
Cross-plane heat transport in thin films with thickness comparable to the phonon mean free paths is of both fundamental and practical interest. However, physical insight is difficult to obtain for the cross-plane geometry due to the challenge of solving ...
Hua, Chengyun, Minnich, Austin J.
core   +1 more source

Fourier transformation and response functions

open access: yes, 2010
We improve on Fourier transforms (FT) between imaginary time $\tau$ and imaginary frequency $\omega_n$ used in certain quantum cluster approaches using the Hirsch-Fye method.
Gunnarsson, O.   +3 more
core   +2 more sources

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

A semi-analytic spectral method for elliptic partial differential equations

open access: yesElectronic Journal of Differential Equations, 2017
In this article we present a semi-analytic method for solving elliptic partial differential equations. The technique is based on using a spectral method approximation for the second-order derivative in one of the spatial directions followed by ...
Ishtiaq Ali, Maliha Tahseen Saleem
doaj  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Improved semi-analytical method for air curtains prediction

open access: yesEnergy and Buildings, 2013
Peer ...
Giráldez García, Héctor   +3 more
openaire   +3 more sources

On equivalence of discrete-discrete and continuum-discrete design sensitivity analysis [PDF]

open access: yes
Developments in design sensitivity analysis (DSA) method have been made using two fundamentally different approaches as shown. In the first approach, a discretized structural finite element model is used to carry out DSA.
Choi, Kyung K., Twu, Sung-Ling
core   +1 more source

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