Results 81 to 90 of about 13,909,288 (337)

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

open access: yesFEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima   +8 more
wiley   +1 more source

Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells

open access: yesFEBS Open Bio, EarlyView.
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley   +1 more source

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

open access: yesFEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page   +4 more
wiley   +1 more source

Study on the Time Domain Semi Analytical Method for Horizontal Vibration of Pile in Saturated Clay

open access: yesApplied Sciences
Under the framework of Biot porous media theory, a fractional order Kelvin model is used to describe the rheological effects of soil skeletons, and a coupled vibration model of saturated clay and a pile foundation is constructed. The Laplace transform is
Xin Ren, Li-an Wang
doaj   +1 more source

Analyze the multi-wire magnetic field of HGMS by semi-analytical method

open access: yesResults in Physics, 2018
In this paper, a semi-analytical method (SAM) to analyze the magnetic field distribution in High-Gradient Magnetic Separation (HGMS) was promoted, constituting a combination of conform mapping (includes Schwarz-Christoffel (S-C) mapping) and finite ...
Mei Yuan   +3 more
doaj   +1 more source

Application of X-ray Microtomography to Quantify the Liquid Fraction of M2 Steel for Semi-solid Forming process [PDF]

open access: yes, 2013
Thixoforging, one variant of semi-solid metal processing in which the metallic alloys are processed at low liquid fraction (0.1< Fl < 0.3), is used to produce complex parts with high mechanical properties.
GU, Guochao   +4 more
core   +1 more source

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