Addressing Unmet Medical Needs in Drug Development: Assessment and Implications for Regulatory and Clinical Development Strategies. [PDF]
Domingo-Esteban C +2 more
europepmc +1 more source
ABSTRACT Policy process research has excelled in explaining structural policy change within national settings, but extensions and applications to the EU level have long proven challenging for scholars. Given that the EU is currently experiencing its longest period of Treaty stability since the 1980s—having evolved into a sui generis political system ...
Vassilis Karokis‐Mavrikos
wiley +1 more source
Identification of differentially expressed genes in RNA-seq data via semi-rigid orthogonal sparse KL-NMTF. [PDF]
Gargano G +4 more
europepmc +1 more source
ABSTRACT Objective The early response effect, defined as a reliable symptomatic improvement during the initial phase of treatment, is the most robust predictor of recovery following eating disorder treatment. This study aimed to investigate which symptom domains mostly influence the early response effect. Methods Data from N = 232 adult patients (90.8%
Ammara Imtiaz +3 more
wiley +1 more source
Pisotriquetral arthrodesis for the management of chronic pisotriquetral fracture-dislocation: a case report. [PDF]
Nicolaï T +3 more
europepmc +1 more source
ABSTRACT This research was conducted within the framework of project SI2.825082, funded by the European Commission—DG GROW. The project's objective was to finalise a European approach for assessing the fire performance of façades under medium and large fire exposure conditions.
Péter Tóth +7 more
wiley +1 more source
Development and Experimental Validation of a Physics-Based Digital Twin for Railway Freight Wagon Monitoring. [PDF]
Cascino A +7 more
europepmc +1 more source
All the bedrooms a stage: Reconceptualizing sex as “performance” to sex as “rehearsal”
Abstract In the United States, sex is often spoken about in terms of performance, and naturally invokes language of theatricality. Sexual performance has been used as an umbrella term to refer to sexual satisfaction, behavior, embodiment, and also pathology in terms of conditions such as erectile dysfunction.
Taylor Harmon
wiley +1 more source
Intelligent Condition Monitoring of High-Formwork Support Systems: A Hybrid FEM-Deep Learning Approach with Large Language Model Integration. [PDF]
Zhao L, Mbachu J, Liu L, Zhang R.
europepmc +1 more source
Electronic jelly: Engineering the mechanics of hydrogels for flexible electronics
By unifying mechanical reinforcement strategies—double networks, structural ordering, and dynamic interactions—this review demonstrates how engineered hydrogels can transcend their fragility to achieve the strength, toughness, and reliability required for flexible electronics, including wearable sensors, energy devices, and soft robotic systems ...
Tianfu Zheng +2 more
wiley +1 more source

