Results 41 to 50 of about 1,920 (253)

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Trivial Homology Groups of Warped Product Semi-Slant Submanifolds in Kenmotsu Space Forms

Axioms
This paper investigates the relationship between homology groups and warped product semi-slant submanifolds in Kenmotsu space forms. Some rigidity theorems for vanishing homology groups on warped product semi-slant submanifolds are obtained using the ...
Noura M. Alhouiti, Ali H. Alkhaldi, Akram Ali, Fatemah Mofarreh, Piscoran Laurian-Ioan   +4 more
doaj   +1 more source

Estimation of inequalities for warped product semi-slant submanifolds of Kenmotsu space forms

Journal of Inequalities and Applications, 2016
In this paper, we construct the geometric inequalities for the squared norm of the mean curvature and warping functions of warped product semi-slant submanifolds in Kenmotsu space forms. The equality cases are also discussed.
Misbah Liaqat, Piscoran Laurian-Ioan, Wan Ainun Mior Othman, Akram Ali, Abdullah Gani, Cenap Ozel   +5 more
doaj   +1 more source

Proper Semi-Slant Pseudo-Riemannian Submersions in Para-Kaehler Geometry

International Electronic Journal of Geometry, 2022
In this paper, we examine the proper semi-slant pseudo-Riemannian submersions in para-Kaehler geometry and prove some fundamental results on such submersions. In particular we obtain curvature relations in para-Kaehler space forms. Moreover, we provide examples of proper semi-slant pseudo-Riemannian submersions.
Esra Başarır Noyan, Yılmaz Gündüzalp   +1 more
openaire   +3 more sources

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Gradient Expanding Ricci Solitons Type Inequalities on Submanifolds in Quaternion Kaehler Manifolds with Bi-Slant Factor

Mathematics
In this article, we study the Ricci soliton on quaternion bi-slant submanifolds of quaternion Kaehler manifolds. We obtain a lower-bound-type inequality in terms of expanding gradient Ricci solitons with a gradient-type vector field for the quaternion bi-
Ali H. Hakami, Mohd Danish Siddiqi
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source