Results 151 to 160 of about 33,134 (302)

Exploring AAV‐Mediated Gene Therapy for Inner Ear Diseases: from Preclinical Success to Clinical Potential

open access: yesAdvanced Science, Volume 12, Issue 33, September 4, 2025.
Current preclinical studies of AAV‐mediated gene therapy explore different strategies based on the characteristics of inner ear diseases. For genetic hearing loss, approaches include the replacement of a “good gene,” removal of a “bad gene,” or direct correction of mutations through base editing.
Fan Wu   +7 more
wiley   +1 more source

Motion cue effects on pilot tracking [PDF]

open access: yes
The results of two successive experimental investigations of the effects of motion cues on manual control tracking tasks are reported. The first of these was an IFR single-axis VTOL roll attitude control task.
Ringland, R. F., Stapleford, R. L.
core   +1 more source

Worth the Effort: Lessons for Discovery and Care From an Unusual Case of Gorlin Syndrome

open access: yesAmerican Journal of Medical Genetics Part A, Volume 197, Issue 9, September 2025.
ABSTRACT Gorlin‐Goltz Syndrome (GGS) is a rare autosomal dominant genetic disorder encompassing a diverse range of clinical manifestations, including congenital anomalies and predisposition to cancer. Pathogenic variants in PTCH1 and SUFU account for up to 79% and 6% of cases, respectively. Currently, an estimated 15%–27% of individuals with a clinical
V. Taliercio   +13 more
wiley   +1 more source

The Effect of Sleep Deprivation on the Vestibulo‐Ocular Reflex and Vestibular Adaptation in Healthcare Night‐Shift Workers

open access: yesThe Laryngoscope, Volume 135, Issue 9, Page 3364-3370, September 2025.
This study examined the effects of sleep deprivation on the vestibulo‐ocular reflex (VOR) in healthcare night‐shift workers. Results showed a significant reduction in VOR gain (7.5%) during passive head movements toward far targets after a night shift, whereas other VOR functions and gaze stability remained unaffected.
Nir Livneh   +6 more
wiley   +1 more source

Fistula of Semicircular Canal [PDF]

open access: yesProceedings of the Royal Society of Medicine, 1926
openaire   +3 more sources

Analysis of etiology and clinical features of spontaneous downbeat nystagmus: a retrospective study

open access: yesFrontiers in Neurology
ObjectiveTo investigate the topical diagnosis, possible etiology and mechanism of spontaneous downbeat nystagmus (sDBN) patients with dizziness/vertigo.MethodsThe clinical features of dizziness/vertigo patients accompanied with DBN were retrospectively ...
Sai Zhang   +10 more
doaj   +1 more source

Biophysical evaluation of the human vestibular system Semiannual status report, 1 Jul. - 31 Dec. 1966 [PDF]

open access: yes
Physical properties of labyrinth fluids in human vestibular ...
Meiry, J. L., Young, L. R.
core   +1 more source

Risk of Benign Paroxysmal Positional Vertigo Modified by Diuretics—A Population‐Level Case‐Control Study

open access: yesOtolaryngology–Head and Neck Surgery, Volume 173, Issue 3, Page 613-625, September 2025.
Abstract Objective This study aims to characterize diuretic use among patients with and without benign paroxysmal positional vertigo (BPPV) using a population‐level database. Study Design A case‐control study. Setting TriNetX US Collaborative Network. Methods Subjects with ≥1 hospital visit between 2019 and 2024 were queried and stratified by age (18 ...
Marwin Li   +2 more
wiley   +1 more source

A Low-Dimensional Model of Coordinated Eye and Head Movements [PDF]

open access: yes, 1994
Eye and head movement data, were recorded under head fixed and head-free conditions, and compared with theoretical results obtained using a nonlinear model of eye-head coordination.
Clarke, A.H., Przybyszcwski, A.W.
core   +1 more source

Identification of Differential Metabolites in Chronic Suppurative Otitis Media With Non‐Targeted and Targeted Metabolomics Approach

open access: yesSmart Medicine, Volume 4, Issue 3, September 2025.
Untargeted metabolomics is used to analyze tissue samples from chronic suppurative otitis media patients with or without cholesteatoma and identify metabolic differences across groups stratified by CT scores. Targeted metabolomic validation in an independent cohort verified five candidate metabolites. ABSTRACT Chronic suppurative otitis media (CSOM) is
Lidan Hu   +9 more
wiley   +1 more source

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