Results 141 to 150 of about 24,097 (251)

Staging and cell detection of seminiferous tubules using neural networks [PDF]

open access: yes
Spermatogenesis is a complex differentiation process that takes place in the seminiferous tubules. A specific organization of spermatogenic cells within the seminiferous epithelium enables a synchronous progress of germ cells at certain steps of ...
Heikkinen, Olli
core  

Low retinoic acid levels mediate regionalization of the Sertoli valve in the terminal segment of mouse seminiferous tubules. [PDF]

open access: yesSci Rep, 2021
Imura-Kishi K   +9 more
europepmc   +1 more source

High Uric Acid Promotes Stem Leydig Cell Senescence by CCDC90B Mediates Mitochondrial Quality Control Imbalance

open access: yesCell Proliferation, EarlyView.
In hyperuricemia, uric acid inhibits CCDC90B ubiquitination degradation by binding to it. Excessive CCDC90B induces mitochondrial calcium overload, leading to mitochondrial quality control imbalance and ultimately resulting in SLC senescence and decreased testosterone levels.
Jiayu Huang   +8 more
wiley   +1 more source

Wt1 Is Required for the Regression of Müllerian Ducts in Male Mice by Inducing Wif1 and Osx Expression

open access: yesCell Proliferation, EarlyView.
Wt1 expressed in the MD mesenchyme promotes MD regression by inducing Wif1 and Osx transcription. In male mice, mesenchyme‐specific inactivation of Wt1 results in MD retention. ABSTRACT In mammals, Müllerian ducts (MDs) are the precursors of the female reproductive tract which regress in males during embryonic development.
Min Chen   +12 more
wiley   +1 more source

Quantitative Analysis of the Cellular Composition in Seminiferous Tubules in Normal and Genetically Modified Infertile Mice [PDF]

open access: yes
The aim of this study was to establish a quantitative standard for the cellular composition in seminiferous tubules at each stage of spermatogenesis in the mouse testis, and thereby evaluate abnormalities in the infertile mouse testis.
Iseki, Shoichi   +3 more
core  

Testicular torsion in foals and stallions

open access: yesEquine Veterinary Education, EarlyView.
Summary Testicular torsion is a rare condition in horses characterised by a change in the position of the testis due to the testicular mesentery twisting around its own axis; it can occur both when the testis is still in the abdominal cavity and when it has descended into the scrotum.
C. P. Bartmann
wiley   +1 more source

Humanin ameliorates diabetes‐induced testicular damage in a streptozotocin‐induced mouse model

open access: yesExperimental Physiology, EarlyView.
Abstract Diabetes mellitus is a major metabolic disorder closely associated with oxidative stress and male reproductive dysfunction. Humanin, a mitochondria‐derived peptide, has been reported to exert cytoprotective, anti‐apoptotic and antioxidant effects in various disease models; however, its role in diabetes‐induced testicular damage remains unclear.
Munevver Gizem Hekim   +2 more
wiley   +1 more source

Morfometrical analysis of diameters of leydig cells nuclei and seminiferous tubules at cryptorchid testes of young males [PDF]

open access: yes, 2009
Leydigove stanice smještene su u intersticijskom tkivu testisa između sjemenskih kanalića. Istraživanje je obuhvatilo biopsije kriptorhičnih testisa petnaestorice muškaraca (18 do 27 god). Kao kontrola poslužili su uzorci tkiva testisa dvojice muškaraca (
Jagić, Anamarija
core  

Preserved Spermatogenesis and Hormonal Function in Men Receiving a Pretomanid Regimen (BPaMZ) for Pulmonary Drug‐Resistant Tuberculosis

open access: yesClinical Pharmacology &Therapeutics, Volume 120, Issue 2, Page 501-509, August 2026.
Pretomanid is a component of the World Health Organization‐recommended treatment regimen for drug‐resistant tuberculosis in patients aged ≥ 14 years. While preclinical rodent studies identified testicular toxicity as a potential clinical liability at elevated doses, no corresponding effects were observed in nonhuman primates nor clinical hormone ...
Pauline Howell   +13 more
wiley   +1 more source

Morphological alterations in the seminiferous tubules of adult Wistar rats: the effects of prenatal ethanol exposure [PDF]

open access: yes, 2004
This study presents the effects of prenatal ethanol exposure on the morphology of the seminiferous tubules of the testes in the adult male rat. Timed-pregnant adult female Wistar rats (average weight 200 g) were given daily intragastric intubation of 5.8
EA, Caxton-Martins   +1 more
core   +1 more source

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