Results 81 to 90 of about 24,482 (261)

A c-KIT codon 816 mutation, D816H, in the testicular germ cell tumor: case report of a Japanese patient with bilateral testicular seminomas. [PDF]

, 2005
Mutations of the c-KIT gene have been reported not only in gastrointestinal stromal tumors and mast cell tumors, but also in testicular germ cell tumors (TGCTs).
Kishimoto, Koji, Mitsuya, Toshiyuki, Suzuki, Takao, Tate, Genshu   +3 more
core   +1 more source

Downregulation of Chromosome 19 miRNA Cluster and the Tumor‐Suppressive Role of miR‐517a‐3p in Choriocarcinoma

Cancer Science, EarlyView.
Chromosome 19 microRNA cluster was downregulated in choriocarcinoma compared with complete hydatidiform mole. miR‐517a‐3p reduced the proliferation, migration, and invasion abilities of choriocarcinoma cell lines. Downregulation of SRSF1, targeted by miR‐517a‐3p, suppressed the malignant potential of choriocarcinoma cell lines. ABSTRACT Choriocarcinoma
Yuki Nishiko, Kosuke Yoshida, Yuko Yasui, Akira Yokoi, Masami Kitagawa, Eri Inami, Masato Yoshihara, Kazumasa Mogi, Yukari Nagao, Satoshi Tamauchi, Nobuhisa Yoshikawa, Kimihiro Nishino, Eiko Yamamoto, Kaoru Niimi, Hiroaki Kajiyama   +14 more
wiley   +1 more source

Anaplastic Variant of Classical Seminoma of the Testis: Northern Israel Oncology Center Experience and Brief Review of Literature

Rambam Maimonides Medical Journal, 2014
Objectives: There are only sporadic reports on the clinical behavior and appropriate treatment of anaplastic seminoma. This retrospective study summarizes our experience with the anaplastic variant of classical (typical) seminoma.
Moshe E. Stein, Jamal Zidan, Tomer Charas, Karen Drumea, Rahamim Ben-Yosef   +4 more
doaj   +1 more source

Unusual case of classic testicular seminoma in a 90-year-old patient: a case report

Journal of Medical Case Reports, 2020
Background Seminoma is the most common subtype of testicular cancer and occurs most commonly in patients aged 30–49 years, but decreases to a very low level in men in their 60s or older. Case presentation A 90-year-old Syrian man with a 6-year history of
Ahmad Al-Mousa, Mohammad Nour Shashaa, Mohamad Shadi Alkarrash, Mohamad Alkhamis, Lina Ghabreau, Mouhsen Dandal   +5 more
doaj   +1 more source

Low‐grade glial neoplasms of germ cell origin may represent maturation of embryonic‐type neuroectodermal elements

Histopathology, EarlyView.
Our results support that low grade glial tumours of germ cell origin (LGGTs) represent a phenomenon of maturation (either spontaneous or induced by therapy) of embryonic‐type neuroectoderm, being possibly equivalent to teratoma from a biological perspective.
João Lobo, Nuno Tiago Tavares, Fernanda Fernandes‐Pontes, Carmen Jerónimo, Rui Henrique, Yiying Yang, Matija Snuderl, Melissa Hruby, Muhammad T Idrees, Thomas M Ulbright, Andres M Acosta   +10 more
wiley   +1 more source

Protein Expression of PTTG-1, OCT-4, and KLF-4 in Seminoma: A Pilot Study

Frontiers in Endocrinology, 2019
Seminomas are the most frequent kind of testicular germ cell tumors (TGCTs), accounting for 50% of tumor diagnosis in young men, whereas non-seminomas account for 40% and mixed forms for 10% of cases. It is currently supposed that TGCTs evolve from a pre-
Giuseppe Grande, Giuseppe Grande, Domenico Milardi, Domenico Milardi, Maurizio Martini, Tonia Cenci, Gaetano Gulino, Francesca Mancini, Antonio Bianchi, Alfredo Pontecorvi, Alfredo Pontecorvi, Francesco Pierconti   +11 more
doaj   +1 more source

Interdisciplinary evidence-based recommendations for the follow-up of testicular cancer patients: a joint effort [PDF]

, 2010
Detailed recommendations for the treatment of testicular cancer exist and due to the stringent application of the standard therapies, most patients can nowadays be cured.
Beyer, J, Cathomas, R, De Santis, M, Gillessen, S, Helbling, D, Lorch, A, Mayer, F, Rentsch, C, Rothermundt, C, Seifert, H-H, Shahin, O, Stenner, F, Zaugg, K   +12 more
core   +1 more source

A successful in vitro fertilization outcome in a hermaphrodite male

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 424-425, April 2025.
Shima Elbakhit M. E. Albasha, Sami Saadi Al‐Said, Haitham Tharwat M. H. El Bardisi   +2 more
wiley   +1 more source

Impact and Risk Factors of Diagnostic Delay in Patients With Testicular Cancer: A Multicenter Retrospective Study

International Journal of Urology, EarlyView.
ABSTRACT Background Testicular cancer progresses rapidly, and delays in diagnosis after symptom onset may lead to disease progression and increased treatment resistance. In this study, we aimed to evaluate the impact of diagnostic delay on various clinical outcomes and identify risk factors associated with delayed diagnosis in patients with testicular ...
Kazuki Honda, Taketo Kawai, Satoru Taguchi, Taichi Shiratori, Jimpei Miyakawa, Yu Nakamura, Tomoyuki Kaneko, Kentaro Suzuki, Shohei Suda, Jun Kamei, Shigenori Kakutani, Aya Niimi, Yuta Yamada, Shinji Urakami, Hiroshi Fukuhara, Tohru Nakagawa, Haruki Kume   +16 more
wiley   +1 more source

Unusual renal and colonic mass: Description of a rare case

Indian Journal of Medical and Paediatric Oncology, 2019
Seminoma is a germ cell tumor which accounts for approximately 40% of all germ cell tumors. Testicular seminoma is usually localized to the testis, and in 25% of cases, lymph node metastasis is seen. However, rarely, it can metastasize to visceras.
Manika Khare, Arvind Ahuja, Minakshi Bhardwaj, Nikhil Khattar   +3 more
doaj   +1 more source