Results 91 to 100 of about 4,708 (179)

New York State Climate Impacts Assessment Chapter 03: Agriculture

Annals of the New York Academy of Sciences, Volume 1542, Issue 1, Page 146-213, December 2024.
Abstract Agriculture is a vital industry in New York State, which ranks among the top‐producing states for dairy, fruits, and several other commodities. As agriculture depends on the weather and specific climatic conditions, this sector faces extraordinary challenges as New York's climate changes.
Deborah Aller, Allison M. Chatrchyan, Alejandro Calixto, Jaime Cummings, Ariel Ortiz‐Bobea, Gregory Peck, Junior Schouten, Benjamin Weikert, Elizabeth Wolters, Amanda Stevens   +9 more
wiley   +1 more source

New York State Climate Impacts Assessment Chapter 10: Water Resources

Annals of the New York Academy of Sciences, Volume 1542, Issue 1, Page 561-619, December 2024.
Abstract Clean, abundant water is essential to the health of New York State's residents, ecosystems, and economy. This critical natural resource faces numerous challenges associated with climate change, including potential impacts on the quality and quantity of source waters—both surface waters and groundwater.
Kelsey Leonard, Stephen B. Shaw, Abraham Francis, David Hermann, Laureline Josset, Christine L. May, Benjamen Wright, Kiyoko Yokota, Amanda Stevens   +8 more
wiley   +1 more source

Complete genome sequence analysis of Seneca Valley virus-001, a novel oncolytic picornavirus

Journal of General Virology, 2008
The complete genome sequence of Seneca Valley virus-001 (SVV-001), a small RNA virus, was determined and was shown to have typical picornavirus features. The 7280 nt long genome was predicted to contain a 5′ untranslated region (UTR) of 666 nt, followed by a single long open reading frame consisting of 6543 nt, which encodes a 2181 aa polyprotein. This
Laura M, Hales, Nick J, Knowles, P Seshidar, Reddy, Ling, Xu, Carl, Hay, Paul L, Hallenbeck   +5 more
openaire   +2 more sources

Commodity risk assessment of Betula pendula and Betula pubescens plants from the UK

EFSA Journal, Volume 22, Issue 11, November 2024.
Abstract The European Commission requested the EFSA Panel on Plant Health to prepare and deliver risk assessments for commodities listed in Commission Implementing Regulation (EU) 2018/2019 as ‘High risk plants, plant products and other objects’. This Scientific Opinion covers plant health risks posed by plants of Betula pendula and B.
EFSA Panel on Plant Health (PLH), Antonio Vicent Civera, Paula Baptista, Anna Berlin, Elisavet Chatzivassiliou, Jaime Cubero, Nik Cunniffe, Eduardo de la Peña, Nicolas Desneux, Francesco Di Serio, Anna Filipiak, Beata Hasiów‐Jaroszewska, Hervé Jactel, Blanca B. Landa, Lara Maistrello, David Makowski, Panagiotis Milonas, Nikos T. Papadopulos, Roel Potting, Hanna Susi, Dirk Jan Van Der Gaag, Andrea Battisti, Claude Bragard, Christer Sven Magnusson, Hugo Mas, Daniel Rigling, Massimo Faccoli, Alžběta Mikulová, Fabio Stergulc, Eugen Christoph, Olaf Mosbach‐Schulz, Franz Streissl, Paolo Gonthier   +32 more
wiley   +1 more source

A Novel Live Attenuated Vaccine Candidate Protects Against Heterologous Senecavirus A Challenge

Frontiers in Immunology, 2019
Senecavirus A (SVA) is an emerging picornavirus causing vesicular disease (VD) clinically indistinguishable from foot-and-mouth disease (FMD) in pigs. Currently there are no vaccines currently available for SVA. Here we developed a recombinant SVA strain
Bishwas Sharma, Bishwas Sharma, Maureen H. V. Fernandes, Maureen H. V. Fernandes, Maureen H. V. Fernandes, Marcelo de Lima, Marcelo de Lima, Lok R. Joshi, Lok R. Joshi, Lok R. Joshi, Steve Lawson, Diego G. Diel, Diego G. Diel, Diego G. Diel   +13 more
doaj   +1 more source

Endoplasmic reticulum stress in diseases

MedComm, Volume 5, Issue 9, September 2024.
The endoplasmic reticulum (ER) serves as a vital organelle in eukaryotic cells, performing essential roles such as protein folding, modification, and trafficking, lipid biosynthesis, and calcium regulation. Various conditions may disrupt ER function, potentially leading to the accumulation of unfolded and misfolded proteins, and triggering ER stress ...
Yingying Liu, Chunling Xu, Renjun Gu, Ruiqin Han, Ziyun Li, Xianrong Xu   +5 more
wiley   +1 more source

Limited availability of methods for the detection of xenotransplantation‐relevant viruses in veterinary laboratories

Xenotransplantation, Volume 31, Issue 3, May/June 2024.
Abstract Background The German Xenotransplantation Consortium is in the process to prepare a clinical trial application (CTA) on xenotransplantation of genetically modified pig hearts. In the CTA documents to the central and national regulatory authorities, that is, the European Medicines Agency (EMA) and the Paul Ehrlich Institute (PEI), respectively,
Joachim Denner
wiley   +1 more source

Viral protease binds to nucleosomal DNA and cleaves nuclear cGAS that attenuates type I interferon

mBio
Nuclear cyclic GMP-AMP synthetase (cGAS) binds to nucleosome with high affinity to prevent its activation by self-DNA. Upon stimulation with double-stranded DNA, cGAS is activated and translocates from the nucleus to the cytoplasm, guided by its N ...
Lei Wu, Ya Yan, Ye Yuan, Zhenchao Zhao, Weiyu Qu, Xiangyu Huang, Haiwei Wang, Pingwei Li, Xin Li   +8 more
doaj   +1 more source

A systematic review of early phase studies for children and young people with relapsed and refractory rhabdomyosarcoma: The REFoRMS‐SR project

International Journal of Cancer, Volume 154, Issue 7, Page 1235-1260, 1 April 2024.
What's new? Rhabdomyosarcoma is the most common soft tissue cancer in children, and around one‐third of patients will have relapse or refractory disease. Here, the authors reviewed early phase studies of relapsed/refractory rhabdomyosarcoma, conducted between 2000 and 2021, to provide accurate information to clinicians and families seeking treatment ...
Connor Evans, Lucy Shepherd, Gemma Bryan, Helen Fulbright, Scott Crowther, Sara Wakeling, Andy Stewart, Claire Stewart, Julia Chisholm, Faith Gibson, Bob Phillips, Jessica E. Morgan   +11 more
wiley   +1 more source

Improving oncolytic adenoviral therapies for gastrointestinal cancers and tumor initiating cells [PDF]

, 2010
Although the treatment of most cancers has improved steadily, only few metastatic solid tumors can be cured. Despite responses, refractory clones often emerge and the disease becomes refractory to available treatment modalities.
Kangasniemi, Lotta
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