Preliminary Evaluation of Protective Efficacy of Inactivated Senecavirus A on Pigs [PDF]
Life, 2021 Senecavirus A (SVA), formerly known as Seneca Valley virus (SVV), causes vesicular symptoms in adult pigs and acute death of neonatal piglets. This pathogen has emerged in major swine producing countries around the world and caused significant economic ...
Yuwan Li +14 more
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Senecavirus cetus a novel picornavirus isolated from cetaceans represents a major host switching to the marine environment. [PDF]
Npj VirusesSenecavirus A (SVA), an emerging virus that causes vesicular disease in swine, was, until recently, the only member of the Senecavirus genus (Picornaviridae).
Vernygora O +6 more
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ZFP36 Facilitates Senecavirus A (SVA) replication by inhibiting the production of type I interferon. [PDF]
Virus ResZinc finger proteins (ZFPs) play an important role in the host-virus interplay. Zinc finger protein 36 is a member of the zinc finger protein 36 family, which includes two other paralogs, namely ZFP36L1 and ZFP36L2. Studies have demonstrated that ZFP36L1
Yin M, Guan L, Zhang M, Li X, Qian P.
europepmc +2 more sources
Identification of a B-Cell Epitope in the VP3 Protein of Senecavirus A [PDF]
Viruses, 2021 Senecavirus A (SVA) is a member of the genus Senecavirus of the family Picornaviridae. SVA-associated vesicular disease (SAVD) outbreaks have been extensively reported since 2014–2015.
Mi Chen +4 more
doaj +3 more sources
Development of a differentiating of infected from vaccinated animal (DIVA) ELISA to detect antibodies against Senecavirus A in pigs using two expression systems of non-structural proteins. [PDF]
Vet QSenecavirus A (SVA) is the causative agent associated with porcine idiopathic vesicular disease (PIVD), a condition indistinguishable from other foreign vesicular diseases affecting pigs.
Watcharavongtip P +3 more
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A neutralizing nanobody-based liquid-phase blocking ELISA to assess the protective potency of Senecavirus A vaccine. [PDF]
Appl Microbiol BiotechnolSenecavirus A (SVA) causes swine blister diseases in the crown of hooves, abortion syndrome, and increased mortality rates in piglets. Vaccination is the best defense against SVA infection.
Mu S +10 more
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Senecavirus A as an Oncolytic Virus: Prospects, Challenges and Development Directions
Frontiers in Oncology, 2022 Oncolytic viruses have the capacity to selectively kill infected tumor cells and trigger protective immunity. As such, oncolytic virotherapy has become a promising immunotherapy strategy against cancer.
Dankun Luo +13 more
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Immunogenicity of an Inactivated Senecavirus A Vaccine with a Contemporary Brazilian Strain in Mice [PDF]
VaccinesSenecavirus A (SVA) is a picornavirus that is endemic in swine, causing a vesicular disease clinically indistinguishable from other vesicular diseases, like foot-and-mouth disease. The widespread viral circulation, constant evolution, and economic losses
Amanda de Oliveira Barbosa +7 more
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Senecavirus A 3C Protease Mediates Host Cell Apoptosis Late in Infection [PDF]
Frontiers in Immunology, 2019 Senecavirus A (SVA), an oncolytic picornavirus used for cancer treatment in humans, has recently emerged as a vesicular disease (VD)-causing agent in swine worldwide.
Maureen H. V. Fernandes +5 more
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Pathogenesis and control of Senecavirus A in swine [PDF]
, 2021 Senecavirus A (SVA) is a nonenveloped, single-stranded, positive-sense RNA virus in the family Picornaviridae. It was first discovered as a cell culture contaminant in 2002 but had been identified in US swine samples dating back to the late 1980s. Since swine were presumed to be the natural host, pigs were experimentally inoculated, but did not develop
Buckley, Alexandra Christine
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