Results 41 to 50 of about 1,525 (194)

Development of an indirect ELISA using a novel linear epitope at the C-terminal region of the VP2 protein to specifically detect antibodies against Senecavirus A

open access: yesVirology Journal, 2022
Background Senecavirus A (SVA) is a pathogen that has recently caused porcine idiopathic vesicular disease (PIVD). The clinical signs are similar to those of foot-and-mouth disease, porcine vesicular disease, and vesicular stomatitis.
Zhongyuan Ma   +3 more
doaj   +1 more source

Engineering His-Tagged Senecavirus A for One-Step Purification of Viral Antigens

open access: yesVaccines, 2022
Senecavirus A (SVA) is a picornavirus that causes vesicular disease in swine, and the inactivated vaccine is used to prevent and control SVA infection.
Junhao Fan   +8 more
doaj   +1 more source

Adaptive Immune Responses following Senecavirus A Infection in Pigs [PDF]

open access: yesJournal of Virology, 2018
ABSTRACT Senecavirus A (SVA), an emerging picornavirus of swine, causes vesicular disease (VD) that is clinically indistinguishable from foot-and-mouth disease (FMD) in pigs. Many aspects of SVA interactions with the host and the host immune responses to infection, however, remain unknown.
Mayara F. Maggioli   +6 more
openaire   +2 more sources

The porcine piRNA transcriptome response to Senecavirus a infection

open access: yesFrontiers in Veterinary Science, 2023
IntroductionSenecavirus A (SVA) belongs to the genus Senecavirus in the family Picornaviridae. PIWI-interacting RNAs (piRNAs) are a class of small Ribonucleic Acids (RNAs) that have been found in mammalian cells in recent years. However, the expression profile of piRNAs in the host during SVA infection and their roles are poorly understood.MethodsHere,
Chen Wang   +20 more
openaire   +3 more sources

Novi VP2/VP3 rekombinantni senekavirus A izoliran u sjevernoj Kini [PDF]

open access: yes, 2023
Senecavirus A (SVA), previously called the Seneca Valley virus, is the only member of the genus Senecavirus within the family Picornaviridae. This virus was discovered as a serendipitous finding in 2002 and named Seneca Valley virus 001 (SVV-001). SVA is
Han, Hong   +12 more
core   +2 more sources

Expert opinion on the identification, risk assessment, and mitigation of microorganisms and parasites relevant to xenotransplantation products from pigs

open access: yesXenotransplantation, Volume 30, Issue 5, September/October 2023., 2023
Abstract Xenotransplantation has the potential to address shortages of organs available for clinical transplantation, but concerns exist regarding potential risks posed by porcine microorganisms and parasites (MP) to the health of human recipients. In this study, a risk‐based framework was developed, and expert opinion was elicited to evaluate porcine ...
Huybert Groenendaal   +14 more
wiley   +1 more source

Crystal structure of Senecavirus A 3C protease [PDF]

open access: yes, 2020
AbstractSenecavirus A (SVA), an emerging picornavirus in porcine population, could infect porcines of all age group and cause FMD-like symptoms. Picornaviridae, a group of RNA viruses do harm to both human and stocks; however, most of picornaviruses are lack of effective vaccines and drugs.
Meng, Kaiwen, Zhang, Lijie, Meng, Geng
openaire   +1 more source

Assessment on the efficacy of methods 2 to 5 and method 7 set out in Commission Regulation (EU) No 142/2011 to inactivate relevant pathogens when producing processed animal protein of porcine origin intended to feed poultry and aquaculture animals

open access: yesEFSA Journal, Volume 21, Issue 7, July 2023., 2023
Abstract An assessment was conducted on the level of inactivation of relevant pathogens that could be present in processed animal protein of porcine origin intended to feed poultry and aquaculture animals when methods 2 to 5 and method 7, as detailed in Regulation (EU) No 142/2011, are applied.
EFSA Panel on Biological Hazards (BIOHAZ)   +25 more
wiley   +1 more source

Rescue of NanoLuc luciferase-expressing Senecavirus A with oncolytic activity

open access: yesVirus Research, 2021
Senecavirus A (SVA), previously known as Seneca Valley virus, is classified into the genus Senecavirus in the family Picornaviridae. SVA is not pathogenic to normal human cells, but has potent oncolytic activity in some tumor cells with neuroendocrine feature, such as small cell lung cancer (SCLC) NCI-H446 cell line.
Fuxiao, Liu   +4 more
openaire   +2 more sources

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