Results 21 to 30 of about 1,611 (231)
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Pré-senescentes, uma nova realidade : que desafios para o serviço social? [PDF]
, 1994 Intervenção social. - ISSN 0874-1611. - N. 10 (1994). - p. 69-83O presente artigo constituí uma breve síntese de uma pesquisa, esta traduz-se na primeira abordagem da prática profissional dos Assistentes Sociais com indivíduos pré-senescentes'.
Ramos, Maria de Fátima +3 more
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Revista Brasileira de Ciência do Solo, 2007 Este trabalho teve como objetivo mensurar a velocidade de decomposição e de liberação de nutrientes in situ de resíduos da cultura do feijoeiro (Phaseolus vulgaris L.).
Eduardo Chagas +3 more
doaj +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Revista de Pesquisa Cuidado é Fundamental Online, 2021 Objetivo: analisar as produções científicas acerca da participação dos idosos integrantes de Centros de Convivência para Idosos e a influência destes na qualidade de vida dos participantes.
Anne Carolinne Marie dos Santos Gomes +5 more
doaj +4 more sources
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
, 2023 Seminário de Iniciação Científica e Tecnológica. Universidade Federal de Santa Catarina. Centro de Ciências da Saúde. Departamento de Ciências Morfológicas.Sabe-se que a carcinogênese oral não é dependente exclusivamente de mutações genéticas nas ...
Thiesen, Letícia
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Liberación de sustancias en células senescentes [PDF]
, 2012 La invención trata de nanodispositivos para la liberación controlada de sustancias que comprenden un soporte recubierto por oligosacáridos, donde dichos oligosacáridos comprenden al menos 3 unidades de monosacáridos, y donde al menos uno de los ...
Murguía, José Ramón +9 more
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