Results 161 to 170 of about 365,500 (282)

Insights into Aβ and Presenilin from a Canine Model of Human Brain Aging

Neurobiology of Disease, 2002
In this review, we describe insights into β-amyloid (Aβ) production using aged dogs as a model of human brain aging. The advantage of using dogs is that they naturally accumulate Aβ neuropathology with age.
Elizabeth Head, Reidun Torp
doaj  

In vivo localization of human acetylcholinesterase-derived species in a β-sheet conformation at the core of senile plaques in Alzheimer's disease. [PDF]

J Biol Chem, 2019
Jean L, Brimijoin S, Vaux DJ.
europepmc   +1 more source

The growth rate of senile plaques is determined by the competition between the rate of deposition of free Aβ aggregates into plaques and the autocatalytic production of free Aβ aggregates [PDF]

A. V. Kuznetsov
openalex   +2 more sources

Senile Plaques [PDF]

, 2011
openaire   +1 more source

Presenile Alzheimer dementia characterized by amyloid angiopathy and large amyloid core type senile plaques in the APP 692Ala→Gly mutation [PDF]

, 1998
Patrick Cras, F. van Harskamp, Lydia Hendriks, C. Ceuterick, Cornelia M. van Duijn, S Stefanko, Albert Hofman, J. M. Kros, Christine Van Broeckhoven, Jean‐Jacques Martin, F. van Harskamp   +10 more
openalex   +1 more source

microRNA-132/212 deficiency enhances Aβ production and senile plaque deposition in Alzheimer’s disease triple transgenic mice

, 2016
Julia Hernandez-Rapp, Sara Rainone, Claudia Goupil, Véronique Dorval, Pascal Y. Smith, Martine Saint‐Pierre, Maxime Vallée, Emmanuel Planel, Arnaud Droit, Frédéric Calon, Francesca Cicchetti, Sébastien S. Hébert   +11 more
openalex   +1 more source

Aβ-Aggregation-Generated Blue Autofluorescence Illuminates Senile Plaques as well as Complex Blood and Vascular Pathologies in Alzheimer's Disease. [PDF]

Neurosci Bull
Fu H, Li J, Zhang C, Du P, Gao G, Ge Q, Guan X, Cui D.   +7 more
europepmc   +1 more source

P4‐151: Sulphate moieties of heparan sulphate proteoglycans associated with senile plaques in Alzheimer's disease [PDF]

, 2008
Ilona B. Bruinsma, Tom J.G. Gevers, Toin H. Van Kuppevelt, Guido David, Robert M.W. de Waal, Marcel M. Verbeek   +5 more
openalex   +1 more source

Enrichment of cholesterol in microdissected Alzheimer’s disease senile plaques as assessed by mass spectrometry [PDF]

, 2009
Maı̈ Panchal, Jacqueline Loeper, Jack‐Christophe Cossec, Claire Perruchini, Adina N. Lazar, Denis Pompon, Charles Duyckaerts   +6 more
openalex   +1 more source

P3‐056: Atorvastatin and pitavastatin improve cognitive function and reduce senile plaque and phosphorylated tau in aged APP mice [PDF]

, 2011
Kōji Abe, Tomoko Kurata, Kazunori Miyazaki, Miki Kozuki, Nobutoshi Morimoto, Yasuyuki Ohta, Yoshio Ikeda, Tohru Matsuura   +7 more
openalex   +1 more source