Results 231 to 240 of about 365,500 (282)
Some of the next articles are maybe not open access.
Senile plaques in temporal lobe epilepsy
Acta Neuropathologica, 1994Senile plaques (SP) are one of the characteristic pathological lesions of Alzheimer's disease (AD). They are also seen in the brains of some non-demented individuals as an age-related change. Identification of clinical conditions associated with these "incidental" SP could provide insight into AD pathogenesis.
Laurie A. Miller, Ian R. A. Mackenzie
openaire +2 more sources
Archives of Neurology And Psychiatry, 1936
In spite of a great deal of study, both histopathologic and histochemical, no agreement has been reached as to the exact origin of the characteristic plaques that occur in the brain in cases of senile dementia. A survey of the extensive literature indicates that the hypotheses concerning the histogenesis of these senile plaques may be briefly listed as
C. C. Lee, S. Hiroisi
openaire +2 more sources
In spite of a great deal of study, both histopathologic and histochemical, no agreement has been reached as to the exact origin of the characteristic plaques that occur in the brain in cases of senile dementia. A survey of the extensive literature indicates that the hypotheses concerning the histogenesis of these senile plaques may be briefly listed as
C. C. Lee, S. Hiroisi
openaire +2 more sources
Gallyas-Schiff Stain for Senile Plaques
Biotechnic & Histochemistry, 1992Gallyas technique was modified by a direct application of Schiff's reagent after physical development, resulting in distinctive staining of amyloid deposits in argyrophilic structures. With this modified method, senile plaques in Alzheimer's disease are clearer. This method is easy to perform and suitable for routine neuropathological examination.
K. Kobayashi +4 more
openaire +3 more sources
Acetylcholinesterase fibers and the development of senile plaques
Brain Research, 1987A new, highly sensitive histochemical technique for actylcholinesterase (AChE) was applied to a study of Alzheimer's disease brain tissue. Many immature senile plaques were seen to be developing along AChE-positive axons in the hippocampus and neocortex. Single fibers often displayed multiple lesions, showing stages of initial swelling, ballooning with
Edith G. McGeer +2 more
openaire +3 more sources
Evidence for Cholinergic Neurites in Senile Plaques
Science, 1984In the neocortices and amygdalae of young and aged macaques, cholinergic axons were identified by means of a monoclonal antibody to bovine choline acetyltransferase. Many fine, linear, immunoreactive profiles were seen in these animals. In the older animals, some cholinergic axons showed multifocal enlargements along their course.
Linda C. Cork +7 more
openaire +3 more sources
Neuroradiology, 2000
I studied the CT appearances and the distribution of 109 asymptomatic calcified senile scleral plaques in 49 patients (98 eyes). The vast majority were just anterior to the insertion of the horizontal rectus muscles. The calcified plaques are variable in size, can be single or multiple, involve one or both eyes, and are only seen in elderly patients ...
openaire +2 more sources
I studied the CT appearances and the distribution of 109 asymptomatic calcified senile scleral plaques in 49 patients (98 eyes). The vast majority were just anterior to the insertion of the horizontal rectus muscles. The calcified plaques are variable in size, can be single or multiple, involve one or both eyes, and are only seen in elderly patients ...
openaire +2 more sources
Senile plaques in aged squirrel monkeys
Neurobiology of Aging, 1987Aged squirrel monkeys develop senile plaques in the brain that are similar to those occurring in aged rhesus monkeys and aged humans. These plaques consist of abnormal, swollen neurites around an amyloid core. In whole-hemisphere coronal sections through the level of the rostral temporal lobe, plaques are present in temporal cortex, amygdala ...
Jerry Sepinwall +6 more
openaire +3 more sources
SENILE HYALINE SCLERAL PLAQUES
Archives of Ophthalmology, 1945The recent literature describes two new lesions of the sclera—one primarily necrotic in origin and the other primarily degenerative in character. Within a period of six months I have observed 5 cases of the latter type. The condition is one of symmetric hyaline degeneration of the sclera, occurring in advanced age and characterized by the presence of ...
openaire +3 more sources
Senile plaques in very aged cats
Acta Neuropathologica, 1996Senile plaques were found in the cerebral cortices of three very aged cats (more than 18 years old). The plaques consisted of a coarse assembly of silver staining-positive materials, and was morphologically different from the well-known classical, primitive, and diffuse plaques.
Kazuyuki Uchida +5 more
openaire +3 more sources
Role of microglia in senile plaque formation
Neurobiology of Aging, 1995To assess the role of microglial cells in senile plaque (SP) formation, we examined the density and distribution of microglia in the temporal neocortex of three groups of nondemented individuals, chosen to represent sequential stages of SP formation (no SP, n = 14; diffuse plaques (DP) only, n = 12; both DP and neuritic plaques (NP), n = 14) and ...
Ian R. A. Mackenzie +2 more
openaire +3 more sources