Results 21 to 30 of about 365,500 (282)

Cholesterol Accumulates in Senile Plaques of Alzheimer Disease Patients and in Transgenic APPsw Mice [PDF]

Journal of Neuropathology and Experimental Neurology, 2001
Takashi Mori, D. Paris, T. Town, A. Rojiani, D. Larry Sparks, A. Delledonne, F. Crawford, Laila Abdullah, James A. Humphrey, Dennis W. Dickson, Michael J. Mullan   +10 more
semanticscholar   +2 more sources

The senile plaque: Morphological differences in APP knock‐in mice brains by fixatives

Brain and Behavior, 2023
The morphology of senile plaques depends on the APP knock‐in mice brain fixative. Solid forms of senile plaques were detected in APP knock‐in mice after formic acid treatment with Davidson's and Bouin's fluid fixative as the brain of AD patients.
Rikuya Yoshimura, Tomohiro Miyasaka, Satoru Funamoto, Takashi Saito, Takaomi C. Saido, Masaya Ikegawa, Nobuto Kakuda   +6 more
doaj   +1 more source

In Situ Oxidative Catalysis by Neurofibrillary Tangles and Senile Plaques in Alzheimer’s Disease [PDF]

Journal of Neurochemistry, 2000
L. Sayre, George Perry, Peggy L. R. Harris, Yahua Liu, Kathryn Schubert, Mark A. Smith   +5 more
semanticscholar   +2 more sources

NEURITIC (SENILE) PLAQUES AND FILAMENTOUS CHANGES IN AGED RHESUS MONKEYS

Journal of Neuropathology and Experimental Neurology, 1973
H. Wiśniewski, B. Ghetti, R. Terry
semanticscholar   +2 more sources

Senile Scleral Plaque Mimicking an Intraocular Foreign Body. [PDF]

Cureus
Muhammad H, Chan WS, Jaafar J, Wan Hitam WH.   +3 more
europepmc   +2 more sources

Effect of the electro-acupuncture on senile plaques and its formation in APP⁺/PS1⁺ double transgenic mice. [PDF]

Genes Dis, 2019
Yang Q, Zhu S, Xu J, Tang C, Wu K, Wu Y, Wang Y, Sheng H.   +7 more
europepmc   +2 more sources

Neurofibrillary tangles and the deposition of a beta amyloid peptide with a novel N-terminal epitope in the brains of wild Tsushima leopard cats. [PDF]

PLoS ONE, 2012
Beta amyloid (Aβ) deposits are seen in aged individuals in many of the mammalian species that possess the same Aβ amino acid sequence as humans. Conversely, neurofibrillary tangles (NFT), the other hallmark lesion of Alzheimer's disease (AD), are ...
James K Chambers, Kazuyuki Uchida, Tomoyuki Harada, Masaya Tsuboi, Masumi Sato, Masahito Kubo, Hiroaki Kawaguchi, Noriaki Miyoshi, Hajime Tsujimoto, Hiroyuki Nakayama   +9 more
doaj   +1 more source

Extracellular protein components of amyloid plaques and their roles in Alzheimer’s disease pathology

Molecular Neurodegeneration, 2021
Alzheimer’s disease (AD) is pathologically defined by the presence of fibrillar amyloid β (Aβ) peptide in extracellular senile plaques and tau filaments in intracellular neurofibrillary tangles.
M. M. Rahman, Christofer Lendel
semanticscholar   +1 more source

Microbial involvement in Alzheimer disease development and progression

Molecular Neurodegeneration, 2020
Alzheimer disease (AD) is the most prominent form of dementia and the 5th leading cause of death in individuals over 65. AD is a complex disease stemming from genetic, environmental, and lifestyle factors.
Hannah R. Bulgart, Evan W. Neczypor, Loren E. Wold, Amy R. Mackos   +3 more
doaj   +1 more source

Empagliflozin reduces vascular damage and cognitive impairment in a mixed murine model of Alzheimer's disease and type 2 diabetes [PDF]

, 2020
Background Both Alzheimer's disease (AD) and type 2 diabetes (T2D) share common pathological features including inflammation, insulin signaling alterations, or vascular damage.
Alves-Martinez, Pilar, Carranza-Naval, María José, García Alloza, Mónica, Herrera, Marta, Hierro Bujalance, Carmen, Infante-Garcia, Carmen, Lubián López, Simón Pedro, Marco González, Ángel José del, Suarez, Javier   +8 more
core   +1 more source