Results 71 to 80 of about 365,500 (282)
Neuroinflammation in Alzheimer’s disease: microglial signature and their relevance to disease
Inflammation and Regeneration, 2023 Alzheimer’s disease (AD) is the most common form of dementia, pathologically characterized by senile plaques and neurofibrillary tangles (NFTs), resulting in neurodegeneration. Neuroinflammation, defined as the activation of glial cells such as microglia
Akira Sobue, Okiru Komine, Koji Yamanaka
doaj +1 more source
Imaging Studies of Aging, Neurodegenerative Disease, and Alcoholism. [PDF]
, 1995 Neurodegenerative diseases such as Alzheimers disease, disorders such as alcoholism, and the aging process can lead to impaired cognitive function and dementia.
Eberling, Jamie, JAGUST, William J
core
ChemBioChem, EarlyView.This review explores pathological disulfide‐crosslinking as a key driver of amyloidogenic protein misfolding and aggregation. Oxidative and ER stress pathways contributing to disease progression are discussed and emerging therapeutic strategies targeting disulfide‐linked aggregates in neurodegenerative and systemic amyloid diseases are examined ...
Dong Min Kang +4 more
wiley +1 more source
ChemPlusChem, EarlyView.The interaction between iron‐heme and amyloid‐β (Aβ) peptides can be strongly influenced by the cellular compartment. The presence of sodium dodecyl sulfate as a lipid‐mimicking system shows a protective role of the membrane by hindering both the formation of the heme–Aβ complex and the peroxidase‐like activity, reducing the accessibility of the lipid ...
Chiara Bacchella +5 more
wiley +1 more source
Immune mechanism in senile plaque formation
Pathophysiology, 1994 Alzheimer disease (AD) is characterized by the appearance of two very different lesions, senile plaques and neurofibrillary tangles (NFTs). The pathological process which causes the disease must be responsible for both, but how they are linked is still a mystery.
Andis Klegeris +4 more
openaire +2 more sources
ESC Heart Failure, Volume 12, Issue 2, Page 1119-1131, April 2025.Abstract Large clinical data underscore that heart failure is independently associated to an increased risk of negative cognitive outcome and dementia. Emerging evidence suggests that cerebral hypoperfusion, stemming from reduced cardiac output and vascular pathology, may contribute to the largely overlapping vascular dementia and Alzheimer's disease ...
Mauro Massussi +6 more
wiley +1 more source
Music Therapy Techniques for Memory Stabilization in Diverse Dementias [PDF]
, 2018 Music contains certain unmistakable healing properties pertaining specifically to the matured body and soul affected by various types of dementia. Music therapy aids in memory retention or the retarding of the loss of mental function as a result of ...
Shotts, Amanda
core +1 more source
Pan African Medical Journal, 2017 Nous rapportons le cas d'une femme âgée de 75 ans, hypertendue sous traitement, pseudophake au niveau de l'éil droit, cataracte de l'éil gauche et chez qui l'examen ophtalmologique décèle de façon bilatérale et symétrique des zones de dépression sclérale de couleur grisâtre située en avant de l'insertion des deux muscles droits internes.
Amina Berraho, Mohamed Elyadari
openaire +3 more sources
Exploration, EarlyView.BACE1 interfering RNA, metallothionein and ruthenium complexes ([Ru(bpy)2dppz]2+) were all loaded in prussian blue nanoparticles (PRM‐siRNA). PRM‐siRNA under near‐infrared light irradiation showed good photothermal effect and triggered instantaneous opening of blood‐brain barrier for enhanced drug delivery.
Xiaoyuan Ding +9 more
wiley +1 more source
Nanoscale Research Letters, 2019 Background Considering the high incidence of Alzheimer’s disease among the world population over the years, and the costs that the disease poses in sanitary and social terms to countries, it is necessary to develop non-invasive diagnostic tests that ...
Tamara Fernández-Cabada +1 more
doaj +1 more source