Liposomal Delivery of L‐2‐Hydroxyglutarate for Targeting Epigenetic Dysregulation in Osteoarthritis
Osteoarthritis involves cartilage degeneration, inflammation, and epigenetic dysregulation. A liposomal formulation of the TET1 inhibitor L‐2‐hydroxyglutarate to overcome rapid joint clearance was developed. The formulation showed good physicochemical properties, reduced inflammatory and catabolic gene expression in chondrocytes, and alleviated ...
Denise Murgia +10 more
wiley +1 more source
Integrated Plastic Surgery Match Trends After Step 1 Pass/Fail Implementation: Data Analysis and Literature Review. [PDF]
Clark C, Foote K, Frey JD, Burke MS.
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An emerging TIMER-2C framework for addressing barriers to research culture and productivity among local healthcare providers in the Middle East and sub-Saharan Africa: A qualitative study and modified Delphi approach. [PDF]
Odeny B +12 more
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Why and how is private equity involved in assisted living community development and operations? [PDF]
Carder P +9 more
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Photocycloaddition in stilbene‐type salt polymorphs exhibit distinct light‐driven responses: OHT‐TI shows a violent photosalient effect under visible and NIR (two‐photon) irradiation, whereas OHT‐TII reacts statically. Packing and computational analysis reveals that shell‐like structures in OHT‐TI frustrate structural relaxation, accumulating explosive
Emanuela Santagata +10 more
wiley +1 more source
Embryologist experience affects concordance with an artificial intelligence embryo ranking algorithm: benefit of artificial intelligence assistance. [PDF]
Berntsen J +5 more
europepmc +1 more source
A scoping review of force plates in female soccer: The utility, existing practice and identification of knowledge Gaps. [PDF]
Fahey JT +3 more
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Comparative study on the performance and early clinical outcomes of senior and junior orthopaedic surgeons in traditional versus robot-assisted total hip arthroplasty. [PDF]
Wang M +7 more
europepmc +1 more source

