Results 231 to 240 of about 3,444,642 (304)

The HCMV‐encoded miR‐UL36‐3p promotes angiogenesis of endothelial cells by downregulating FOXO3

Animal Models and Experimental Medicine, EarlyView.
This illustration shows the role of hcmv‐miR‐UL36‐3p in endothelial cell angiogenesis. During productive infection, endothelial cells express HCMV‐encoded miRNAs. Viral hcmv‐miR‐UL36‐3p promotes endothelial cell proliferation, migration, and capillary tube formation by directly targeting and downregulating FOXO3. The pro‐angiogenic activity of hcmv‐miR‐
Chen Wang, Mengyu Li, Guosheng Li, Hao Zhang, Cheng Wang, Chen‐Yu Zhang   +5 more
wiley   +1 more source

Sex‐Specific Genetic Architecture of ALS: Evidence of a Female Protective Effect?

Annals of Neurology, EarlyView.
Background Amyotrophic lateral sclerosis (ALS) shows sex differences in incidence and age of onset, yet the underlying biological mechanisms remain poorly understood. Methods We investigated sex‐specific genetic architecture in an Italian ALS cohort with whole‐genome sequencing (1,333 ALS cases, 755 controls).
Maurizio Grassano, Francesca Palumbo, Gabriele Mora, Salvatore Gallone, Giovanni De Marco, Ilaria Merulla, Claudia Paolantonio, Alessandra Maccabeo, Antonio Canosa, Umberto Manera, Rosario Vasta, Barbara Iazzolino, Marcella Testa, Giuseppe Fuda, Paolina Salamone, Giulia Marchese, Federico Casale, Cristina Moglia, Andrea Calvo, Giuseppe Borghero, Adriano Chiò   +20 more
wiley   +1 more source

Delayed Halide‐Rich Molecular Passivation of CsPbCl3 Perovskite Nanocrystals Enables Bright Violet Light‐Emitting Diodes

Angewandte Chemie, EarlyView.
POCl3 enables delayed dual passivation in CsPbCl3 nanocrystals by slowly releasing Cl‐containing and phosphonic species that heal halide vacancies and Pb‐related defects over time. This self‐healing boosts PLQY by >40‐fold, preserves efficient violet emission for over 2 months in air, and yields a record 409 cd m−2 luminance for CsPbCl3 violet LEDs ...
Nadesh Fiuza‐Maneiro, Junzhi Ye, Woo Hyeon Jeong, Rui Xu, Qingyu Wang, Dong Yoon Chung, Robert A. Taylor, Iago López‐Fernández, Bofeng Xue, Akshay Rao, Bo Ram Lee, Yunwei Zhang, Robert L. Z. Hoye, Sergio Gómez‐Graña, Lakshminarayana Polavarapu   +14 more
wiley   +2 more sources

Landscape of Aging Policies in Bangladesh: A Perspective Study. [PDF]

Health Sci Rep
Hossain MJ.
europepmc   +1 more source

The Dynamics of Neurofilament Light Chain in Spinal Muscular Atrophy

Annals of Neurology, EarlyView.
Objective Newborn screening (NBS) for spinal muscular atrophy (SMA) facilitates early diagnosis and treatment for affected individuals. However, fluid biomarkers that provide early insights into disease activity and outcomes in a neonatal cohort and those unable to access (due to reimbursement criteria) or deferring immediate treatment are lacking ...
Arlene D'Silva, Karen Herbert, Lakshmi Balaji, Jia Mei He, Tejaswi Kandula, Hugo A. Sampaio, Hooi‐Ling Teoh, Esther Tantsis, Jihee Sohn, Nancy Briggs, Nickson Ning, Matthew C. Kiernan, Didu S. Kariyawasam, Michelle A. Farrar   +13 more
wiley   +1 more source

Towards functional precision medicine? Evidence standards of organoids as patient-specific models. [PDF]

Hist Philos Life Sci
Green S, Vogt H, Gaillard M.
europepmc   +1 more source

Liposomal Delivery of L‐2‐Hydroxyglutarate for Targeting Epigenetic Dysregulation in Osteoarthritis

Advanced NanoBiomed Research, EarlyView.
Osteoarthritis involves cartilage degeneration, inflammation, and epigenetic dysregulation. A liposomal formulation of the TET1 inhibitor L‐2‐hydroxyglutarate to overcome rapid joint clearance was developed. The formulation showed good physicochemical properties, reduced inflammatory and catabolic gene expression in chondrocytes, and alleviated ...
Denise Murgia, Akshay Pandey, Raffaele Spanò, Bianca Martins Estevão, Roberto Palomba, Greta Avancini, Tamaghna Gupta, Ana Maria Lopez Estevez, Stuart B. Goodman, Nidhi Bhutani, Paolo Decuzzi   +10 more
wiley   +1 more source

Association between body roundness index and strength fitness in senior middle school students. [PDF]

Front Public Health
Chen L, Yu Y, Mao C, Xu J, He Z, Luo H, Zhu J.   +6 more
europepmc   +1 more source

Digital nutrition intervention in Older Americans Act programs impacts knowledge and desire to participate in virtual programming. [PDF]

Front Public Health
Brown RC, Cook MA, Berton Weitnauer R, Long CG, Crane SJ, McLean AD, Samnadda LM.   +6 more
europepmc   +1 more source