Results 111 to 120 of about 1,825,247 (227)

Lipidomic Profile Reconstruction of Therapeutic Membrane Targets Using Physics‐Based Optimization with Limited Activity Data

open access: yesAdvanced Science, EarlyView.
Using a minimal set of experimentally labeled antimicrobial and non‐antimicrobial peptides, we reconstruct the effective lipid composition of a pathogenic membrane ‐demonstrated at the example of bacterial membranes‐ through a physics‐based evolutionary molecular dynamics (Evo‐MD) approach. Optimization based on peptide insertion reveals broad‐spectrum
Maximilian Krebs, Herre Jelger Risselada
wiley   +1 more source

Tumor‐Derived Exosomal circAP2B1 Induces M2 Macrophage Polarization by Enhancing Mitochondrial Homeostasis to Promote Esophageal Squamous Cell Carcinoma Progression

open access: yesAdvanced Science, EarlyView.
ESCC‐derived exosomal circAP2B1 promotes tumor progression by reprogramming mitochondrial metabolism via the ESRRA/KPNA1/MFN2 axis to induce M2 polarization of macrophages. ABSTRACT Esophageal squamous cell carcinoma (ESCC) remodels the immunosuppressive tumor microenvironment via exosome‐mediated intercellular communication.
Yiru Wang   +5 more
wiley   +1 more source

In Situ Programmable Modulation of Hydrogel Stiffness for Stage‐Adaptive Bone Regeneration

open access: yesAdvanced Science, EarlyView.
Near‐infrared (NIR) irradiation triggers Ca2+ release from thermoresponsive nanocarriers, enabling in situ stiffening of an adaptive hydrogel from a soft to a stiff state, thereby sequentially supporting mesenchymal stromal cell stemness and osteogenic differentiation for stage‐adaptive bone regeneration.
Yuxin Yang   +5 more
wiley   +1 more source

COMPOSER's FORUM, Sunday, March 23, 1986 8:00 p.m. Shepherd School Rehearsal Hall

open access: yes, 2019
PROGRAM: Three miniatures for flute sextet / John Thomas -- City fair / Thomas Senning -- Five miniatures for piano solo / Carlyle Sharpe -- Three songs / Susan Wickman ; poetry by Wallace Stevens and Mark Strand -- Drei kleine Klavierstücke / John ...

core  

Rechtbank onbevoegd in renvooiprocedure in verband met procedure in Duitsland

open access: yes, 2020
Renvooiprocedure. Onbevoegdheid rechter. Curator heeft zich niet gesteld in renvooiprocedure. Schuldeiser verzoekt aanhouding in verband met reeds aanhangige procedure in Duitsland, waarna de rolrechter de procedure heeft doorgehaald. Rolbeslissing houdt
Groot, EF, Groot, EF; id_orcid
core  

Heat‐Suppressing Projection Two‐Photon Lithography Enables High‐Throughput Sub‐Micrometer Manufacturing of Biopolymer Hydrogels for Tissue Engineering

open access: yesAdvanced Science, EarlyView.
The iLEAP technique integrates high‐throughput two‐photon lithography with extrusion printing, bridging sub‐micrometer precision and macroscopic scaffold fabrication. By employing a low‐exothermic photoinitiator, it mitigates thermal damage to biopolymers and preserves bioactivity.
Qifeng Guan   +11 more
wiley   +1 more source

The structure of civil proceedings – convergence through the main hearing model?

open access: yes, 2018
Traditionally, European civil procedure systems have displayed a range of structures. Currently, systems are converging around the main hearing model, which international soft law initiatives on civil procedure also endorse.
Nylund, Anna
core  

The Direction of Amending the Criminal Procedure Act Following the Reform of Investigative Structure: Focusing on Arrest and Detention

open access: yes
In March 2026, following the State Council’s passage of The indictment office Act and Act on the organaization and operation of the Serious Crimes Investigation Agency, the legislative reform of the investigative structure now hinges solely on the ...
The Korean Association of Criminal Procedure Law   +1 more
core   +1 more source

Groundwater Rise Sustains the World's Largest Alpine Water System Under Global Warming

open access: yesAdvanced Science, EarlyView.
Shallow groundwater depth (SGWD) across the non‐permafrost plains of the Qinghai–Xizang Plateau decreased at averagely 0.02 m year−1, adding 31.44 Gt of freshwater storage from 2000 to 2020 and sustaining ∼53 500 km2 of alpine ecosystems. A vadose‐zone capacity of 426.6 Gt reveals these aquifers as promising reservoirs, highlighting groundwater's ...
Jianqing Du   +15 more
wiley   +1 more source

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