Air quality improvement masks global cooling from CO<sub>2</sub> reductions under China's carbon neutrality policies for half a century. [PDF]
Zhao B +18 more
europepmc +1 more source
Endogenous Amplification of Apoptosis via p53 Regulation using a Cascade Nanocatalytic Medicine
An engineered MOF nanomedicine (MAL) triggers cascade nanocatalysis in tumors, converting H2O2 and L‐Arg into cytotoxic peroxynitrite. This induces DNA damage, activates the p53 pathway, and amplifies mitochondrial apoptosis via the BAX/Bcl‐2/Caspase‐3 axis, effectively inhibiting colorectal cancer growth with high biocompatibility.
Tan Wu +8 more
wiley +1 more source
Mid-upper arm circumference cut-offs identifying malnourishment and risk of mortality among patients with tuberculosis. [PDF]
Patsche CB +4 more
europepmc +1 more source
Paraventricular CRF neurons in the hypothalamus project to glutamatergic neurons of the spinal trigeminal caudal nucleus, enhancing neuronal activation and CRFR2 signaling. This pathway increases CRF release and excitatory drive, promoting central sensitization and migraine‐related behaviors. Targeting the PVN–SP5C circuit provides a potential strategy
Jiang Bian +13 more
wiley +1 more source
Performance of Artificial Intelligence Models in Radiographic Image Analysis for Predicting Hip and Knee Prosthesis Failure: A Systematic Review. [PDF]
Stuani R +5 more
europepmc +1 more source
Bilirubin as a Modulator of WNK1 Protein Signaling: Implications for Neuroinflammatory Diseases
ABSTRACT Previously regarded merely as a potentially harmful waste product of heme catabolism, bilirubin has now emerged as a pleiotropic molecule with potent antioxidant, anti‐inflammatory, and hormone‐like properties. Recent findings have revealed protective effects against cardiovascular, metabolic, autoimmune, and neoplastic diseases, as well as ...
Sri Jayanti +3 more
wiley +1 more source
Isfahan Artificial Intelligent 2024 Competitions. [PDF]
Rabbani H.
europepmc +1 more source
This work successfully fabricated ion‐conductive hydrogels with low hysteresis and high conductivity using 3D printing technology. By adjusting the component ratios, the properties of the hydrogels can be tuned to meet diverse sensing requirements. Finally, a multimodal sensing sign language recognition system was constructed based on this hydrogel ...
Quan Hu +9 more
wiley +1 more source
Impact of physical activity on sleep in adults recovering from substance use disorders: a protocol for an N-of-1 observational study. [PDF]
Thal S +9 more
europepmc +1 more source

