Results 141 to 150 of about 997,952 (298)

Placement-Dependent Accuracy of a Smartphone-Based Sensor Application Compared to an Accelerometer-Based System for Measuring Physical Activity in Healthy Adults: A Validation Study. [PDF]

Sensors (Basel)
Garval M, Pedersen L, Pedersen LM, Nielsen AKWDJ, Christiansen DH, Lange J, Wagner S.   +6 more
europepmc   +1 more source

SAA/FPR2 Signaling Between Pericentral Hepatocytes and Macrophages Exacerbates Zonated Liver Transplant Injury

Advanced Science, EarlyView.
After liver transplantation, ischemia‐reperfusion injury is more severe in pericentral regions. Multiomic analyses of human grafts and mouse models identify FOXO1 activation in pericentral hepatocytes as an upstream driver of SAA secretion. SAA recruits and activates FPR2+ macrophages, amplifying local inflammation. Amilo‐5MER inhibits SAA bioactivity,
Feng Zhang, Rong Li, Tingting Wang, Jianhao Zhang, Zhengqi Wu, Qiang You, Xuying Liu, Cuicui Xiao, Jiebin Zhang, Haitian Chen, Jiaqi Xiao, Jia Yao, Jun Zheng, Yingcai Zhang, Hua Li, Shuhong Yi, Yang Yang, Qi Zhang, Xiaofeng Yuan, Yasong Liu   +19 more
wiley   +1 more source

Du potentiel sémantique au signifié dialogique

Arts et Savoirs, 2012
Francesco La Mantia
doaj   +1 more source

Optimized CAP cut-offs for metabolic dysfunction associated steatotic liver disease in patients living with obesity: a large biopsy-based prospective study. [PDF]

Sci Rep
Soliman R, Elbasiony M, Helmy A, Mikhail N, Ezzat H, Gad AM, Halim EA, Zalata K, Masoud R, Hassan A, Farahat A, El Emam M, Shiha G.   +12 more
europepmc   +1 more source

Piezo1 Channel Mediates Mechanically Programmable Drug Delivery to Potentiate Intravesical Chemotherapy

Advanced Science, EarlyView.
This study utilizes programmable mechanical pressure as a therapeutic enhancer to establish a mechano‐chemotherapy strategy. Controlled pressure activates the mechanosensitive ion channel Piezo1 in bladder cancer, triggering a calcium ion cascade that transiently and reversibly amplifies membrane permeability to chemotherapeutics.
Minghai Ma, Xing Li, Minxuan Jing, Zezhong Yang, Jiale He, Jianpeng Li, Xiao Liang, Yunzhong Jiang, Rou Huang, Yuanquan Zhang, Yuanchun Pu, Jiawei Xiu, Yutong Chen, Kaibo Mi, Pu Zhang, Lei Wang, Jinhai Fan   +16 more
wiley   +1 more source

Nuclear translocation of β-catenin in Wg/Wnt signaling via the IFT-A microtubule-associated complex requires Pasovec/Gid8 proteins. [PDF]

Sci Adv
Vuong LT, Mlodzik M.
europepmc   +1 more source

Mechanoadaptation via Myosin Cytoplasmic Redistribution Protects Circulating Tumor Cells From Shear‐induced Death During Hematogenous Dissemination

Advanced Science, EarlyView.
This study investigates how CTCs survive varying shear stress during hematogenous metastasis. We uncover a self‐protection mechanism, by which non‐adherent CTCs adapt to high shearing milieu through accumulated cytoplasmic myosin‐mediated disruption of myosin‐actin binding, attenuating force transmission into chromatin to protect CTCs from shear ...
Cunyu Zhang, Qianchun Wang, Keming Li, Guanshuo Hu, Ying Xin, Kai Tang, Bing Hu, Pengyu Du, Renwei Mao, Baohua Ji, Youhua Tan   +10 more
wiley   +1 more source

Advances in donor-derived cell-free DNA monitoring for solid organ transplantation. [PDF]

Front Immunol
Sairafi D, Foord E, Pettersson L, Uhlin M.   +3 more
europepmc   +1 more source

Sens, excès de sens, négation du sens

Actes Sémiotiques, 2011
openaire   +1 more source

L’histoire de vie entre sens et non-sens [PDF]

, 2004
Legrand, Michel
core   +1 more source